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Fighting Dementia with Sea Hero Quest
No comments yetPosted in Game ReviewsNov 29, 2016
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As we move around in the world we develop a sense of how to get from A to B. This relies heavily on the hippocampus, a brain structure nestled deep within each of the temporal lobes, responsible for many functions vital to cognition such as memory and navigation. This is the brain structure famed for becoming physically larger as a result of all the practice driving around London that the drivers of London’s famous Black Cabs have to accrue before they can pass “The Knowledge.” Whilst their memory for the 25,000 roads and 20,000 major landmarks that enable them to instantly reel off the route they’d take to get from one place to another is extraordinary, for the 33% of those born in 2015 will live long enough to develop dementia at some point in their lives this situation is reversed. Difficulties with navigation, even familiar routes between places visited many times before, is one of the problems in daily life that can herald the approach of full-blown dementia. Understanding the normal trajectory of changes in navigational ability over the lifetime of a health brain is a vital first step. With or without dementia our abilities to memories complex routes becomes slowly but surely compromised by the normal processes of age-related cognitive decline. We need to know what is normal for each age group before we could be in a position to use a steeper than normal decline in navigational ability as an early warning signal, ideally before any memory deficits have had a chance to rear their ugly heads. As our understanding of the metabolic processes that lead to various forms of dementia improve, this early warning could prove to be a vital mechanism in triggering prophylactic treatments early enough to slow down disease progression.
Hugo Spiers, a memory researcher and neuroscientist at University College London, launched a smartphone game in 2016 called Sea Hero Quest, which aims to do just this. Over 2.5 million people have played this surprisingly fun, engaging and challenging game so far, generating the equivalent of an astonishing 9,400 years worth of lab data. The game involves memorising a map of waterways around which a series of numbered buoys have been distributed. Once you’ve planned the journey you’re going to make and tucked it away in your working memory, the map is then taken away and your job is then to steer your little fishing boat (increasingly customisable as you progress through the game) by tapping the left or right side of the touch screen. The terrain varies from idyllic sandy paradises to rainy, foggy, bumpy rides across perpetually undulating swell. Thanks to the funding from Deutsche Telekom and Glitchers – the tech-gurus who actually created the game – the graphics are beautifully rendered, the gameplay is smooth and unlike most games designed to answer important scientific questions, every aspect of the user experience is highly polished. As was the delivery of the first results announced at SfN 2016 and summarised below by the man himself…
Personally I was surprised by how hard some of the levels were. I play a lot of brain training games (e.g. PEAK Review, BRAIN AGE 2 Review ), just to keep myself up to date on the latest offerings, and am now accustomed to finding myself able to get maximal scores on most categories of games pretty quickly through daily play. Not Sea Hero Quest. Once I got past the easier earlier levels, I often found myself getting lost in the mist, or going round and round in circles having forgotten how to get from buoy 3 to buoy 4. As a consequence, not only did I help scientists like Hugo Spiers and colleagues from the University of East Anglia and Alzheimers Research UK to generate data (anonymously, you only have to give your age) but I also got an insight into what the future might have in store for me should I become one of the unfortunate 1 in 3 that get clobbered by dementia in my post-retirement years. As you progress from level to level you periodically get to chase down one of a large variety of sea monsters. Having dodged innumerable obstacles along the way the monster in question eventually leaps out of the water at you and your task, is to resist the temptation to hit the button on your camera to take a photo of the rare and exotic sea beast in question, until the very last second when the captured image is at its most aesthetically pleasing.Overall, I found playing this game great fun, very challenging at times and doubly satisfying knowing that it would, in some small but meaningful way, help science to get some much needed answers about how the human brain keeps track of where it is and where it’s going in health, so we can better understand when this system breaks down in disease.
I would just like to take a moment to applaud @HugoSpiers and collaborators for finding a way to genuinely enable people to #gameforgood. Hats off to you all… your Cannes Lion was thoroughly well deserved!In addition to these monthly blogs you can get daily brain tweets about other amazing developments in the world of neuroscience by following me on Twitter (@DrJackLewis). And for a fortnightly appraisal of the latest quirkly stories from the wonderful world of science on general there’s always the totally free Geek Chic Weird Science podcast available from iTunes, Podbay, Libsyn and many others.
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Hot Topics in Neuroscience by Dr Jack
No comments yetPosted in Brain Tweet ArchiveJan 28, 2015
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On an annual basis I copy a year’s worth of Tweets and paste them into a blog post to preserve them for posterity. Turns out I’m going to have to start doing this biannually. Why? Because Twitter now only seems to allow access only to the last 6 months worth.Where all those tweets from earlier years have gone I may never know. But assuming that they’ve all been deleted then I’m relieved that I’ve been archiving them myself. This is because, for me, Twitter serves a valuable role in terms of enticing me to find and flag the three most interesting brain research stories from that day. I’d have been very sad to have lost my chronology of favourite breakthroughs and curiosities from the world of neuroscience because I find it useful resource for several reasons (and you might too):
1) Whenever I’m reminded of something I’ve read in the past I often want to go back to the original article to refresh my memory with the details. The re-visiting process helps me consolidate my knowledge and integrate it with other evidence that I’ve come across during the intervening period. I find that internet search engines are pretty useless in this regard. Any particular search term will invariably return huge amounts of relevant information. Far too much to wade through to be genuinely useful when the goal is to track down a specific, but perhaps obscure, article.
2) Having a separate record of the articles that I thought were interesting, insightful and/or useful enough to bother the Twitter-sphere with also enables me to keep track of which areas of neuroscience are making the greatest strides forward. So this year I finally took the time to categorize and tally as many of my recent Brain Tweets as I could get my hands on to clarify what topics have been the hottest in recent times.
This chart features only those blog categories that contained 10 items or more. Unsurprisingly given that it’s a weekly podcast tweets relating to Geek Chic’s Weird Science topped the bill with nearly 50 (click here if you’d like to download all episodes, for free!).In 2nd place came the Brain Tech category which includes anything relating to augmenting sick or healthy brains with some kind of man-made technology. Implanted electrodes, direct brain-to-brain intercontinental communication, zapping brains with electrical currents, stem cell therapies and so on.
In 3rd place came the Brain Illness category. This encompasses tweets about developments in all neurological and psychiatric maladies excluding brain injuries and dementia. These each have their own category due to the large numbers of articles I tweeted about on these topics.
In 4th place with 30 tweets came the Drugs category meaning articles that I thought were of broad interest relating to psychoactive drugs (i.e. those that can get into and affect the brain).
Many neuroscientists have been getting their knickers in a twist about the rise of Brain Training games despite scant evidence to back up most of the developers claims so it comes as no surprise that this topic should have stolen 5th place. Neuroplasticity was just two places behind and is a category that I reserve for articles relating to behaviour-induced changes in brain structure and function that are unrelated to commercial Brain Training. I’m not going to bore you by explaining every single category but I should point out that Bad Journo is a category for articles that I thought were misleading / poorly written or articles written to correct / clarify misleading journalistic communications.
So now you have a sense of what each of these categories mean you can now navigate this half year’s worth of brain tweets accordingly and hopefully find what your interested in more easily. Categories in order of most to least often tweeted about are:
Geek Chic, Brain Tech, Brain Illness, Drugs, Brain Train, Brain Imaging, Neuroplasticity, Sleep, Creativity, Neuroscientists, Brain Injury, Senses, Dementia, Neuroanatomy, Bad Journo, Brain Art, Eating, Events, Brain Food, Emotion, Young Brains, Brain Health, Memory, Other Brains, Quotes, Holding Onto Marbles, Neurodevelopment, Evolution, Music, Sex, Altruism, Brain Ageing, Brain Hacks, Gut bacteria, Language, Books, Fun, Learning, Neurosurgery, Reward Pathways, Addiction, Artificial Intelligence, Gaming, Optical illusions, Talks, Vision, Brain Education, Coding, Decisions, Heuristics, Mind over Matter, Navigation, Neuromarketing, Pain, Parenting, Stress, Brain-Gender, Consciousness, Exercise, Habits, History, Intelligence, Morality, Personality, Politics, Reviews, TV, Window to the Soul, Body Language, Film, Free will, Hallucination, Immunity, Impulses, Interview, Meditation, Neuromyths, Poverty, Religion
Listed below, in alphabetic order, for your convenience:
Addiction
Quitting smoking leads2release of hormone at heart of stress response (CRF) in key part of brain reward pathway (VTA) http://bit.ly/1xiXeXU
The cycle of addiction – this simple but beautiful animation says it all
Use of e-cigarettes does not discourage, and may encourage, conventional cigarette use among US adolescents @JAMAPeds
Workaholism: The Addiction of this Century — via #Neuroscience News – http://bit.ly/1oRkfbY
Altruism
“necessary role for prefrontal control in generating honest behavior by overriding our tendencies2be self-interested” http://bit.ly/1qf7Nsc
Extraordinary altruists and their oversized amygdalae – would you give a kidney to a stranger for nothing in return? http://n.pr/1C45T1e
People give more generously when the advertising focuses on a needy individual rather than the masses: http://n.pr/13H2Jok
Amazing role reversal in altruistic behaviour (homeless man giving taxi money2damsel) inspires many acts of kindness http://huff.to/1wTEgpv
How the environment impacts childrens’ tendency to be altruistic http://stanford.io/17D7d1h
Kindling altruism in kids is not just for Christmas – “best way2teach generosity is to show it in your own behaviour” http://bit.ly/1Gw03b1
Artificial Intelligence
It finally happened: A robot beat the Turing Test (@qz) http://bit.ly/1kaeiEO
Google #Brain -snapping up every deep learning expert / business they can get their hands on: http://wrd.cm/1r3Mole
“New landmark in..history of brain-inspired computing” Super-fast processing/low power consumption: http://bit.ly/1lH2Pyw
System uses information on internet2teach robots how2interact with world using Markov models: http://tcrn.ch/1qcATqs
Bad Journo
Part of brain responsible for hangover guilt – is an “intriguing hypothesis” with “no direct implications for humans” http://bit.ly/1pGyt6s
FAIL: “..cause for this behaviour may lie in the “anterior insular cortex”, located behind the forehead.” http://bit.ly/VTK3h2
“Wire your brain for gratitude” – this Forbes article is horrible, it actually made me gag… http://onforb.es/1uASaIw
“Brain GPS” is NOT an “exciting NEW part of.. jigsaw of our brain. O’Keefe’s 1st paper was published in 1971!! http://bit.ly/ZAXRP4
Gambling Addiction Related To Brain Reward System – BBC News I’m ashamed of you – that headline is not “news” http://bbc.in/1CL9n7l
Great example of why people who have only the vaguest understanding of neuroscience shouldn’t write about the brain: http://bit.ly/1k3isUv
‘Sci-Fi or Sci-Fact?’- separating the science fiction from the science fact in the media. http://thescifact.wordpress.com
Humans only use 10% of their #brain, right? Wrong! This myth still lurks, e.g. in new movies like LUCY: http://bit.ly/1rwvtXH #neuroscience
Piece by @m_wall on @TheConversation on ‘cargo cult neuroscience’ in business and education: http://bit.ly/1tAR5Eg
Watson/Crick did not discover DNA. That was Miescher 84yrs earlier. W/C worked out its structure. cc @TheAtlanticTECH
Body Language
Body language – how it works, where to look and why it evolved in the fist place
Books
Reading http://bit.ly/1oBHTtY which resonates with the ‘Gone Fishing’ principle of @polarbearpirate and @DrJackLewis #SortYourBrainOut
Memoirs of a neurosurgeon, essential reading, methinks: http://bbc.in/1qqkvq7
NYT book review covers recent tomes that consider impacts of the internet / related technologies on our minds: http://nyti.ms/1uFoZZK #SYBO
Sort your brain out is @AmazonUK’s Kindle Daily Deal! http://ow.ly/GjrS4 @DrJackLewis @polarbearpirate Get it NOW!
I’m reading Do No Harm by neurosurgeon Henry Marsh – it is without doubt the best book I’ve read this year: http://bit.ly/1eRYZ1K #xmaslist
Brain Ageing
Psychology news Why the Elderly Can Die from a Broken Heart http://ow.ly/2NRdjS
In Men, Long-Term Unemployment May Speed Aging – http://psych.ly/I9JfO6 #mentalhealth #health
Older people find it harder to filter out irrelevant info – but retain the mental flexibility of their former selves: http://bit.ly/1z28tT6
2015 looms large and 2014 has flown by, why our perception of time changes as we get older http://buff.ly/1xkMLwV
Older brains work better early: http://bit.ly/1vf4nJy So elders,plan more cognitively demanding chores for the A.M.
Brain Art
Do you want to showcase your artwork or film? Is it about the brain? Show us and feature in our magazine! #NeuroArt http://youtu.be/7mM_8XbhXOoCake brains! #MoreBrainz http://bit.ly/1qOVEFL
Can the arts and humanities contribute significantly to the study of the brain? http://www.sciencedirect.com/science/article/pii/S0896627314008368 … by Semir Zeki, so the answer is, of course, yes!
Science graphic of the week – depicting how psilocybin (magic mushrooms) change the brain’s (functional) connectivity http://wrd.cm/1rDv6HZ
Warner Bros style public service announcement re: The Perils of Porn Brain = quite amusing:http://huff.to/1wCqlmu
Nice brain collage BBC news – top notch effort: http://bit.ly/1HEb0c0
One for you @DrJackLewis – Artists and neuroscientists join forces: Art Neuro @theragfactory http://bit.ly/1xdBF90
Beautiful complexity “@andyextance: The ‘brainbow’: Cells tagged with fluorescent proteins”
I WANT ONE!! RT @vaughanbell: 3D-printed Christmas tree decorations of own brain http://3dprint.com/31522/3d-printed-brain-ornaments/ … via @Radiolab
Anyone for a helmet studded with crystals that change colour according to #brain state? No? http://huff.to/1qQMH0o #BCI meets #fashion
Micrograph, created by Spike Walker, depicting dopamine crystals illuminated by polarised light | #WellcomeImages | http://blog.wellcome.ac.uk/2014/08/01/image-of-the-week-dopamine/ …
Brain Education
Neurobiology for dummies courtesy of the brain science podcast #neuroscience #SortYourBrainOut #SYBO #brain http://bit.ly/XfdKtG
I heard about MOOCs long ago (Massively Open Online Courses) – now I’ve actually enrolled in 1! At Yale; on morality: http://tinyurl.com/lnmhrl5
Hands up who wants to learn how the brain deals with space? (space around us, not outer space!) Here’s a free course: http://bit.ly/1uMESvv
Brain Nutrition
Study suggests higher levels of omega-3 in diet are associated with better sleep: http://www.psypost.org/?p=23550
Brain Food: Superfoods for ultimate brain power and what to avoid … good video! http://www.youtube.com/watch?v=9KlMxriH4Cg&sns=tw
I love the idea of actively training people to become addicted to healthy food: http://bbc.in/1ur22qB
Fruit and vegetable consumption could be as good for your mental as your physical health http://ow.ly/C035A
vmPFC activity (above bridge of ur nose!) upon viewing different foods is positively correlated with calorie content: http://bit.ly/1rpPyvW
Scientific American made a film which explains why a turkey dinner makes us sleepy. win/fail? http://bit.ly/1xUCkQp
Space-aged brain food put to the test by amusing Guardian blogger: http://bit.ly/1uqnPO1
Recently published paper indicates there are more anti-oxidants in organic than non-organic foods: http://bit.ly/1rf3j49
Eat fish on a weekly basis (don’t stress to much about which type) for your #brain’s sake: http://ti.me/1mh7YgV
Weight loss probiotics? http://bit.ly/1mTl4Ak Does this just allow people2continue keep eating badly;w/out getting fat?
I wonder if cold weather increases glucokinase activity in hypothalamus? I ate a whole pack of Matchmakers last night http://reut.rs/12IcilH
Brain Hacks
“How to debug your brain..”is 1 of the strangest blog posts I’ve ever read. Can’t work out whether that’s good or bad: http://bit.ly/1t7z8ch
How the #brain makes and breaks habits via @SciAmMIND http://bit.ly/1oeyU3H
Exercise may leave you feeling less anxious because you perceive your environments as less threatening http://on.apa.org/1rWHF6O
Some of those “old chestnuts” that reduce cognitive burden in a world of info overload: http://bit.ly/1qLRD6zThe power of the green office: Having plants around increases productivity by 15% http://ow.ly/AWqPz
Brain Health
Power of tumeric @bbchealth: Curry spice ‘helps brain self-heal’ http://bbc.in/1vkvlfG
Novel approach to treating brain cancer boosted by new UK system of extra support for Promising Innovative Medicines: http://bit.ly/1qYbkLB
Former Surgeon General for US also has #SortYourBrainOut message – he advises weekly saunas to sweat off the toxins! http://bit.ly/1qhQR5O
Has anyone out there ever tried Prof Bartlett’s Brain Vitality Index? Interesting? Motivating? http://bit.ly/WJElzb
Ever wondered if small blood vessels in your brain are getting clogged up? Try standing on 1 leg: http://bit.ly/1wKKcCG
If you do this Brain Health check over the Christmas break -consider your booze levels before getting too concerned! http://onforb.es/1CWtWzg
Get out in that glorious sunshine! Even mild Vit D deficiency is assoc with increase risk of dementia: http://bit.ly/1r0RhZW #skin+sun=vitD
Imagine: in the not-too-distant future school kids might be asked2donate blood2help rejuvenate grandparents’ #brains! http://bit.ly/1ADTmAO
Shed some fat to #SortYourBrainOut by reducing its inflammatory impact on #brain tissue (which promotes #Alzheimer’s) http://ti.me/1vSSJk4
Crafts like knitting work the brain to produce flow which can help to ease symptoms in people w/ PTSD,depression etc: http://cnn.it/1uWAxnb
Keeping your heart & blood vessels in good nick leads to better #brain function http://bit.ly/1olanqU #SortYourBrainOut #neuroscience #SYBO
Physical fitness in childhood improves white matter in the brain – Medical News Today: http://www.medicalnewstoday.com/releases/281269.php#.U_tGfu9i1bY.twitter
Pre-natal exposure to phthalates (commonly found in many consumer products) associated with reduced IQ aged 7: http://bit.ly/1Gg2zSL
Brain Illness
Tell-tale signs that you might have a brain tumour (hypochondriacs – do not click here)
Brain tumour pressing against temporal lobe causes uncontrollable laughter (gelastic epilepsy) in girl
Wii Balance Board Induces Changes in the Brains of MS Patients
Autism appears2involve insufficient synaptic pruning resulting in “too many” connection points between brain wires
Disorganised patches of #brain tissue in frontal & temporal lobes may disrupt high level social function in #autism
From lab to real life – environmental enrichment seems to be very helpful for kids with #autism: http://bit.ly/1ltCkSU
Brain degeneracy (it’s good for you!) and people with bits missing from / creatures burrowing through their brains: http://bbc.in/1sJ1X5C
Brains get sick too – teaching kids about mental illness: http://ind.pn/1spdG8S
Default Mode Network (your ego/where you daydream) connections appear to mature more slowly in kids who develop ADHD: http://n.pr/1qXAjx9
Interesting case of a man born with disconnected brain hemispheres
Living With Schizophrenia: The Importance of Routine | NYT
“Alzheimer’s in a Dish” will hopefully accelerate the process of screening new drugs 2treat this devastating illness: http://nyti.ms/ZWyOXv
Autism re-conceived as a disorder of being able to make predictions about what is going to happen next: http://bit.ly/ZdB2AF
Smoking and mental health, what’s the connection? http://www.theguardian.com/science/sifting-the-evidence/2014/jul/15/smoking-and-mental-health-whats-the-connection … Important @soozaphone piece
Take two books and call me in the morning, pediatricians say Great column on prescribing books http://ti.me/1pu7db8 from @anniemurphypaul
Talk about a controversial science topic: paedophile #brain processes child faces differently2others.. http://ind.pn/1oRyDWZ
Tale of discovering that, despite seemingly being a well-adjusted person, you are in fact a psychopath http://bit.ly/1osg9sx
Reduced temporal lobe volumes in #brains of homocidal youth offenders http://bit.ly/1khCUB7
I had no idea that the rate of suicide is much higher amongst men than women – interesting speculations here re: why? http://bit.ly/1xRvq9F
Gene implicated in schizophrenia produces too much protein that prevents dendrites (brain cell “antennae”) from branching out http://fxn.ws/1tq3ruY
Bedside EEG uses graph theory maths to establish whether “anybody’s home?” with patients in vegetative state: http://bit.ly/1CrZnj0
Tumour on pituitary gland causes release of too much growth hormone Can you imagine growing 20cm in just 12 months?! http://dailym.ai/1wIpNLv
Exercise Counteracts Genetic Risk for Alzheimer’s – Scientific American http://buff.ly/1rftlAK
I remember when people were mocked for having Chronic Fatigue Syndrome, now neuroscience defines its brain hallmarks: http://stanford.io/1xEj1Hj
Inspiring story of brain machine interfaces helping people with locked in syndrome communicate with the outside world: http://n.pr/1rINUqk
New Multiple Sclerosis research – make local environment of damaged nerve wrappers more conducive to re-myelination: http://tinyurl.com/prfjvmf
Treating depression w/ implants, tricky given brains are like “a hundred billion people all singing at the same time”
Turning anecdotes of antidepressants killing brain cancers into clinical trials is good e.g. of “no profit, no dice”
When dementia comes early: http://bbc.in/1DThNvO
This piece on face blindness by @KateSzell won the @wellcometrust science writing prize http://gu.com/p/43cta/stw
Tongues are connected directly to the brain stem – electrical stimulation in people with MS can improve their gait! http://bit.ly/1uwXjb9
“Oxytocin…attenuates hyperactive amygdalas in social anxiety disorder…explored as a potential treatment for PTSD”
Are you genetically predisposed to antisocial behaviour?
PTSD can develop even without memory of the trauma: http://www.sciencedaily.com/releases/2014/08/140814123844.htm
Brain Imaging
A major drawback of MRI is that the machines are big, expensive & immovable – enter DOT: http://bit.ly/1hJsni6
“Sounds create visual imagery, mental images, and automatic projections…” Pattern classifier fMRI experiment: http://bit.ly/1inpfTD
Free will emerges from brain “noise” #neuroscience #EEG http://bit.ly/1l2xbyo
The good, the bad and the ugly of fMRI #brain imaging experiments: http://bit.ly/1lq0DOB
“solid evidence that neural measurement can be useful for..prediction of mass preference” #neuroscience http://bit.ly/1rR9oCr
Using MRI2track human brain white matter volume changes from 7-85 show rainbow-like pattern of expansion&contraction: http://bit.ly/1tDz60c
“decreased #brain activation seen with fMRI may help explain why many chemotherapy patients complain of #chemobrain” http://reut.rs/1nC88D1
Discovery of brain’s Default Mode Network is 1 of best examples of key finding that starts with “huh? That’s weird..” http://m.medicalxpress.com/news/2014-10-brain-mind-rest.html
Reduced blood flow2certain brain areas (posterior cingulate) detected with MRI (ASL) warns of dementia risk early on: http://tinyurl.com/MRIdetectsARCD
How to get disproportionate press coverage of your neuroscience study? Get folks2read Harry Potter in an MRI scanner: http://abcn.ws/1HI8dyF
Heard the 1 about where jokes come from? MRI on 22 improv comedians whilst dreaming up amusing captions for cartoons: http://bit.ly/1ydfwbf
NHS Choices doing what they do so well..this time clarifying news articles on MRI studies of chronic fatigue syndrome http://bit.ly/10NVwl4
“Scientists generate tons of data..nobody uses it. We are building the technology to bring all..that together” http://nyti.ms/1kL9yqA #brain
New #brain imaging technique tracks tau tangles of #Alzheimer’s plus new Alz protein identified: http://abcn.ws/Uc70ec #neuroscience
“#brain scans revealed that..amygdala responded differently to subliminal images of trustworthy &untrustworthy faces” http://bit.ly/1y64NOL
DOT – new way to scan brains. Diffuse Optical Tomography shines light into #brain through scalp/skull: http://bit.ly/1sYQZ95 #neuroscience
Using fMRI to capture transition from counting on fingers to just “knowing” the answer to a sum: http://fxn.ws/1rizTou #SYKBO #neuroscience
Neuroscience Study Finds Brain Can Take Quick Call On Trustworthiness http://www.ibtimes.co.uk/neuroscience-study-finds-brain-can-take-quick-call-trustworthiness-1459915 #neuroscience
Brain Injury
Any #brain aneurysm you might have in your noggin=much more likely to burst (haemorrhage) if you smoke http://bit.ly/1tFpKQf
Wide awake man being fitted with Deep Brain Stimulation Electrodes4Parkinson’s – can’t believe they missed 1st time!! http://ab.co/1wd27Ci
Would Neymar be Neymar if he’d followed recommendations for under14’s to “not head the ball in soccer”? http://bit.ly/1poRGtb
Brain Disorders Might Arise from Starving Neurons: http://bit.ly/1qrxdQe
6 yrs of living w/ flashbacks, strange smells, headaches – caused by parasitic worm, living in brain, captured on MRI: http://bit.ly/1t9bSf7
Progress towards new use for MRI in detecting free radicals to assess severity of #brain injuries #neuroscience http://bit.ly/1tL573h
Could American Football Pro’s brain injuries explain violent behaviour off pitch? Is it even above national average? http://nbcnews.to/1wHl541
“Helicopter view” on EEG data allows spreading depolarisation assoc w/ Traumatic Brain Injury2come into sharp relief: http://bit.ly/1ozhcGK
A single season of American Football can damage a kid’s #brain even if they don’t suffer a concussion: http://onforb.es/1l9JPsf #neuroscience
FIFA’s Dazed and Dated Attitude to Head Injuries http://nyti.ms/1nvxYUV – should player with head injury stay on when 3 subs have been used?
Giving erythropoeitin (EPO) to babies born prematurely protects them from #brain damage: http://bbc.in/VN3rfo #neuroscience #SYKBO
How to help babies deprived of oxygen during birth avoid #brain damage? Cool them to 33 degrees C asap: http://bbc.in/1wa99TL #neuroscience
Don’t forget to breathe! Who ever heard of screen apnoea? http://bit.ly/1r00UwN
Inspiring account of woman adapting 2 new life after traumatic #brain injury: http://bbc.in/1ooCRpj #DiaryOfAHeadcase – her title not mine!
Stimulating #brain cells in the motor cortex improves recovery from stroke (in mice using optogenetics) http://bbc.in/YsP15E
Brain Tech
Interesting paper about potential4hackers to access personal data via consumer-grade #brain computer interfaces #BCI http://bit.ly/1lv8QNn
Don’t dabble in DIY-tDCS until you at least know the real risks (watch out for those known unknowns): http://bit.ly/1giqOXw
Chip implanted in paralysed man’s brain (eventually) enables him to move his hand again: http://bit.ly/1q8JvAt
US military to invest in research into brain implant to monitor/remedy psychiatric problems of veterans: http://bit.ly/1rcvt1X
What social media tech does2brains 1st bit very similar to Cyber Heads chapter in #SortYourBrainOut http://bit.ly/1utTCQb
Mind boggling that severe #OCD is treated w/ deep #brain stimulation despite noone really knowing how/why it works: http://cnn.it/UFdPpm
“beginning of a future in which people with paralysis will be able to leave the wheelchair & literally walk again” http://nbcnews.to/1oZ66eZ
Love of Johnny Cash induced when #OCD man’s Deep #Brain Stimulation electrodes tickle his Nucleus Accumbens, but why? http://wapo.st/1neiB9X
“Telepathy or a Painstaking Conversation in Morse Code?” Pierre Mégevand goes beyond the media hype: http://bit.ly/1qHg9ax
“West Virginia Uni…won a $539,000 grant to engineer a wearable scanner to image activities of the brain in motion” http://tinyurl.com/oo3y5xy
How science of social pressure is being leveraged by wearable tech companies to make getting fit a battle with others http://bit.ly/WGO1db
Look mum no hands! Flying a plane using the power of thought alone: http://bit.ly/1CbdH1b News clip of an EEG-manipulated flight simulator
Advanced prosthesis restores sense of touch to amputees http://bbc.in/1vSTD1J
Even Just the Presence of a Smartphone Lowers the Quality of In-Person Conversations #psychology #communication http://www.psmag.com/navigation/nature-and-technology/presence-smart-phone-lowers-quality-person-conversations-85805/
AMAZING: “decoder was able to reconstruct which words several..volunteers were thinking, using neural activity alone” http://bit.ly/1p65zNp
During my NeuroBSc I wrote a theoretical essay about wiring a prosthetic hand into neurons of the arm. We are now one step closer… http://bit.ly/1uAjqeT
Electrodes in to human hippocampus via cheek using bendy,MRI-compatible,robot-controlled needles http://bit.ly/1ocoN3u
People who meditate are better at controlling machines via brain-computer interfaces (BCI) than those who don’t: http://tinyurl.com/ku9m9ww
Can you imagine having ur brain wired into a robotic arm and controlling it just by thinking? From the horse’s mouth: http://bit.ly/1x27NNu
I might get one of these thought-controlled brain chips to squirt dopamine into my reward pathways when I daydream: http://bit.ly/1v3EMDF
Neuromorphic chips take flight enabling miniature drones to learn on the fly (literally): http://bit.ly/1phOMXM
Scary that these brain-to-brain studies essentially treat 2nd person as an inert, arm-twitching, zombie: http://bit.ly/110D4VY #neuroethics
This puts the Q “are you a man or a mouse?” into a new light/brave new world http://bit.ly/1yaywL3 Human astrocytes take over mouse brain..
DIY Brain Zapping Meets the World of Internet Marketing http://bit.ly/1nROJ16
Does controlling the cursor by moving your tongue around in your mouth sound futuristic? Yes? Well – future is here: http://bit.ly/1o5ZWXI
For those who missed this on XFM’s #GeekChic last Sun – wearable robot providing 2extra fingers 4tricky manual tasks: http://bit.ly/1sJLmg6
Progress & stumbling blocks in the development of an implantable chip that might one day boost #memory: http://bit.ly/1wE62Uv #neuroscience
Wearable robotics will really catch on when they produce force illusions to pull hand towards destination, like this: http://bit.ly/1jSZKzZ
“High-tech shower cap” controls glioblastomas 4 longer by disrupting cancer division via local electromagnetic fields http://bit.ly/1EuUgVD
Deaf tech transformation: #GoogleGlass could help deaf communicate @BBCNews http://bbc.in/1qXJbRP
EEG from person1 imagining moving hands/feet (in India) used2induce visual experience via TMS in person2 (in France) http://bit.ly/1tSLqsh
The wisdom in exercising caution with DIY attempts2enhance #brain function w/ TDCS,via the delicious http://bit.ly/1tSLqsh
Deep brain stimulation is big business. Dutch firm Sapiens acquired by Medtronic for $200,000,000 http://on.wsj.com/1q1j92r #DBS #neurosurgery
Navy Uses Exoskeletons for Shipyard Maintenance | Defense Tech http://ow.ly/AGyi1
One for you, @DrJackLewis “@sweatscience: brain stimulation on elite endurance athletes: http://www.outsideonline.com/fitness/bodywork/the-fit-list/Inside-Red-Bulls-Project-Endurance.html?c=n
Philips & Accenture IT team up to develop brain computer interfaces for people with #ALS: http://fxn.ws/1qVyK1c
IBM’s bee brain capacity SyNAPSE chip soon to be released into the hands of universities, next stop – Skynet? http://bit.ly/1AZOs0O
The man who grew eyes’ fascinating piece by @mocost for @guardian http://ow.ly/ALBrX
Brain Training
Old skool Dr Kawashima’s Brain Age re-launched on the Wii U Virtual Console: http://aol.it/1uy3Pch
Brain training package LearningRX claims new data shows transfer of benefits beyond trained skills: http://bit.ly/1j59rUY
Remarkable documentary detailing Navy SEAL training that enables recruits to control their brain’s fear response: http://bit.ly/1pEgs48
Lumosity brain training (which my parents are now hooked on) tries2expand its 60M users thru android: http://bit.ly/1qVNFci
Top ten #brain training apps courtesy of Huffington Post: http://huff.to/1kN3r3G
Most people “know it is possible to maintain a healthy brain, but more than half of respondents admit they don’t know how” http://huff.to/VdC26n
Excellent summary of the issues surrounding Brain Training by @dana_fdn http://dana.org/Cerebrum/2014/The_Brain-Games_Conundrum__Does_Cognitive_Training_Really_Sharpen_the_Mind_/
“Can you really teach people to be mentally tougher?” http://bbc.in/1qK2t0U
Brain training games must play second fiddle to regular exercise & social engagement if you want to #sortyourbrainout http://ti.me/1DxtiKc
Latest brain training app on the block, Berlin cash-backed Memorado, raises $1.3M in seed funding: http://tcrn.ch/1tZOSCz
Meditation suggests that happiness is…a skill, something you can train just [like training] your body in the gym” http://bit.ly/1qmw9B9
Could a Video Game Be the Key to Stroke Recovery? http://ow.ly/C9BSE
Forget brain training games; spend your lunchtime trying to wrap your noggin around these classic mind benders: http://bbc.in/ZLxwh4 #SYBO
If Brain Fit Clubs crossed the pond & popped up in the UK – would anyone go for it? Or could it only work in the USA? http://bit.ly/1shD1PW
Regular exercise helps kids brains,improving ability2 “block out irrelevant information&concentrate on..task at hand” http://tinyurl.com/Play4urBrain
Sort Your Brain Out! @DrJackLewis & @polarbearpirate share their top tips: https://www.youtube.com/watch?v=wS857UVWqPQ&list=UUAvEpbsRFKYkc7zgCU6IHyw (thanks @fifthframe) #SYBO #Brainpower
Time “spent doing solo software drills..not spent hiking, learning Italian..playing w/ ur grandchildren”=not worth it http://bit.ly/1xcSFfj
MUST READ-> Fostering and Measuring Skills: Improving Cognitive and Non-Cognitive Skills to Promote Lifetime Success http://go.shr.lc/1zwSV8I
Expanding working memory boosts fluid intelligence This free game will help you do just that! http://bit.ly/1nZO4Xa #SortYourBrainOut #SYBO
1 hour after waking up from general anaesthetic my spatial working memory has plummeted from ~12 items to ~8.
16hrs after waking from general anaesthetic not only did spatial working memory return2normal but I smashed my Go-NoGo record
BBC article on first results from The Great Brain Experiment @CitizenBrains http://www.bbc.co.uk/news/science-environment-28447177
All the best scientists experiment on themselves 😉 http://bit.ly/1kWicID I’m studying my working memory, are you? #SortYourBrainOut #SYBO
I’m going to master this dual 3-back task if it kills me: http://bit.ly/1nZO4Xa #braintraining #workingmemory #fluidintelligence #SYBO
If, like me, you’ve really struggled with transition from Dual 2-Back to Dual 3-Back.. soldier on!! http://bit.ly/1nZO4Xa #SortYourBrainOut
Took me 50 trials 2 reach Dual 4-Back! If @ first you don’t succeed.. http://bit.ly/1nZO4Xa #braintraining #workingmemory #SortYourBrainOut
Brain train gaming for sporting prowess, anyone? http://bit.ly/1uv2EcK #SortYourBrainOut #SYBO
RE https://twitter.com/sciammind/status/539760126714855424 … Brain Training Doesn’t Make You [Much] Smarter via @sciammind
Computer Coding
Want to help your kids code? Ages 5+ in England will be learning – we’ve got tips for parents: http://ow.ly/B5QfK
If I was 13 I would KILL to do this MT @alomshaha: London parents: UCL are running FREE coding tuition for 13-18yo http://blogs.ucl.ac.uk/ucl-coding-club/
East London Kids To Be Offered Training Loans To Learn Coding http://tcrn.ch/1ybcAh
Consciousness
The claustrum – brain area that appears to be the ON/OFF switch for conscious awareness: http://bit.ly/1pXbUWH
Has team of Max Planck neuroscientists affectionately referred to as “The Greek Mafia” finally cracked consciousness? http://bit.ly/1u2NRtE
Creativity
Extremely thorough account of investigations into links between creative genius and mental illness: http://bit.ly/1qdzWAt
“Creativity is a perversely difficult thing to study” Steven Pinker on fMRI exp on creative writing: http://nyti.ms/1pwI5Ow
Can epilepsy fuel creativity? http://bit.ly/1uU9dIY
http://bit.ly/1oBHTtY is very relevant to Gone Fishing (For Great Ideas) chapter in our book #SortYourBrainOut by @polarbearpirate & myself
Link between creativity & subclinical levels of madness (colloq.) has always rung true to me. Finally some hard data: http://bit.ly/1wm5G6u
Magic of a powerful narrative – a neuro perspective: http://bit.ly/1nMzTf2 Great article from the Mack Daddy of oxytocin – Paul Zak #SYBO
Innovation MYTHS: open-office plans decrease productivity, group brainstorming -> fewer & worse ideas than solo http://www.newrepublic.com/article/118815/innovation-districts-are-oversold-you-cant-engineer-creativity
Why we all need to make time to play: http://www.theguardian.com/lifeandstyle/2014/oct/05/why-play-is-important-to-us-all-lauren-lavern
Imagination and Reality Flow in Opposite Directions in the Brain: http://neurosciencenews.com/eeg-neural-circuit-reality-imagination-1560/
#creativity in decline amongst youngsters despite broadly accepted importance in achieving success: http://onforb.es/1k3HwvE
How do ideas happen? And how do we feed our brains to have more of them? @mattfutureproof gives it some thought: http://futureproof.co.uk/no-idea-about-ideas/
Finding inspiration in your sleep: http://bit.ly/1B8MpsT #SortYourBrainOut #creativity #innovation #SYBO
Robin Williams, 2010 in the Guardian, http://www.theguardian.com/film/2010/sep/20/robin-williams-worlds-greatest-dad-alcohol-drugs
The relationship between mental illness & creativity is not straightforward: http://bit.ly/1r7dr1s #psychology #genius #madness #brain
The War on Fun: How Modern Culture is Killing Creativity http://warriorwriters.wordpress.com/2014/07/31/the-war-on-fun-how-modern-culture-is-killing-creativity/
Why You Should Doodle More. #creativity http://zite.to/1qUI0Y8
Decisions
Not acting fast enough to save Earth from climate change/not saving enough for retirement -caused by same brain flaw? http://bit.ly/1zeU5r6
Excitement and anxiety battling it out in #brain during a decision where you win either way (WIN-WIN): http://bit.ly/1ldofmO #neuroscience
Our “gut feelings” are messages that simplify life decisions for us by guiding our attention toward smarter options.. http://lnkd.in/d3jze79
Dementia
36-pronged approach simultaneously targeting diet, exercise, sleep, brain stimulation improves memory in mild Alz: http://bit.ly/1nJvgm9
Investigating links between mental illnesses / immune system; particularly depression and Alzheimer’s: http://bit.ly/16IzIKo #thankyouHenry
“Puzzles and crosswords could be best way to beat dementia” http://www.express.co.uk/life-style/health/488869/Puzzles-and-crosswords-could-be-best-way-to-beat-dementia
Dose of curcumin (in turmeric) enables eye test4 Alz to catch it early enough4development of new drugs: http://bit.ly/1q9KDou
In 2011, I blogged about potential for arthritis drug to halt Alz: http://bit.ly/Wq88MT Now more new data: http://bit.ly/Wq7W08
Study reveals how gardens could help dementia care http://bit.ly/1l1xGoR
Testing people’s sense of smell may provide clues to accumulation of beta-amyloid plaques of Alzheimer’s: http://bit.ly/1zBSQ6O
Everyone back to bed! Research on how sleep relates to onset of #dementia: http://www.sciencedaily.com/releases/2014/07/140701091458.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fmind_brain%2Falzheimers+%28Alzheimer%27s+News+–+ScienceDaily%29
On the connection btw Alzheimer’s disease, diabetes, and cinnamon — @Alzheimersnet via @APlaceForMom http://bit.ly/1mJWfGw
The value of Exercise: being physically active in middle age may reduce the risk for Alzheimer’s disease in old age http://bit.ly/1uGHRVS
Drugs
In case you missed the chat about chemical Brain Enhancement the first time round: http://bit.ly/1rTaSj9
New study suggests magic mushroom therapy much more effective than nicotine replacement for smoking cessation: http://bit.ly/ZjidMU
Didn’t even realise methamphetamine caused #brain damage, let alone this finding that THC protects against it: http://ti.me/1pmZ8nj
Popular anti-depressant drug (SSRIs), long thought to take weeks to take effect, changes healthy brains in just 3hrs: http://ti.me/Yyrnyt
Antipodean link between cannabis & suicide risk is tenuous. Correlation does not mean causation, explained here: http://bit.ly/XnwGGh
Fantastic article in this month’s The Psychologist by @ProfDavidNutt on therapeutic potential of psychedelic drugs: http://bit.ly/W34JCJ
Finally homing in on truth behind the proposed link between childhood cannabis use & psychosis in later life? http://bit.ly/XFxtCv
In the Q&A after my brain talks one topic consistently seems to pique curiosity: CAFFEINE -so I wrote a blog on it.. http://bit.ly/1ry3qZx
Worth further study? Of 446 adults treated 4 head trauma, lower incidence of death among those testing +’ve for THC: http://bit.ly/1uapOW4
“1 transcendent trip can alter people’s personalities on a long-term basis..making them more open..more appreciative“ http://bit.ly/1zJd0yg
If this wasn’t the NYT/well-written I’d never have retweeted yet another piece entitled “This Is Your Brain On Drugs” http://bitly.com/1thHVvC
Cannabis is orexigenic (i.e. smoking weed gives you the munchies) now we have a better understanding of the mechanism http://bit.ly/1ouaI1s
If your nightly cup of cocoa has a whopping dose of flavanols – it might just improve your memory: http://bit.ly/1wBPorI #SortYourBrainOut
Microbubbles + ultrasound = ferrying drugs across the blood brain barrier: http://bit.ly/1DADhNL
This type of article usually makes me cringe. This 1 didn’t! Brain benefits of green tea etc: http://bit.ly/1t3HINJ #SortYourBrainOut #SYBO
Does cannabis really shrink your brain and compensate by increasing connectivity? NHS Choices set the record straight http://bit.ly/10XXoY5
Electrical brain stimulation 2 – Caffeine 1 http://bit.ly/1vpJb3o
Update on therapeutic uses of MDMA (ecstasy) and psilocybin (mushrooms): http://bit.ly/1p1UmGV #brain #neuroscience
Smart drugs like modafinil don’t make your brain work better if you’re a bright spark: http://bit.ly/1BJoaUN #SortYourBrainOut #SYBO
A little bit of booze improves your sense of smell: http://bit.ly/1np1FLV #neuroscience #SortYourBrainOut #SYBO
Supplementing radiation therapy with cannabinoid drugs slows down the progression of brain cancers even more in mice: http://ind.pn/1vcf9Rj
The bonding hormone oxytocin inhibits the fear center in the brain – http://www.medicalnewstoday.com/releases/285441.php
Finally a proper nootropic on the horizon! Keep an eye on Ana Pereira’s clinical trial of riluzole in mild Alz. http://bit.ly/13tDDIG #SYBO
The American Academy of Neurology calls for more long term studies into therapeutic use of medical marijuana: http://bit.ly/1vBWLfv
#marijuana &your #brain -does it REALLY do significant damage? http://bit.ly/1uwNau1 #neuroscience #hippocampus #amygdala #SortYourBrainOut
Drugs in space and sleepless in the shuttle http://wp.me/ptsTD-7RJ
More on impact of #cannabis use on the adolescent #brain, courtesy of Nature: http://bit.ly/1sz41LV #neuroscience #SortYourBrainOut #SYBO
Great news for drunks! New compound seems to mitigate against the brain damage that results from binge drinking: http://bit.ly/1FKLmRf
Laughing gas shows therapeutic promise in treatment-resistant clinical depression: http://bit.ly/1zHjJ9Z
Smokers have tougher time quitting menthol cigs – menthol alone increases nicotinic receptors in pleasure pathways! http://bit.ly/1IJ86TS
Time for another cuppa? Nice animation from @AsapSCIENCE about caffeine & how it affects your brain http://bit.ly/1qbq7Cd
Eating
“Eating a lot of sugar or other carbohydrates can be hazardous to both #brain structure and function”: http://bit.ly/1pMHgAk
2.1Bn people on Earth are obese/overweight; that’s a lot of narrowed #brain blood vessels : http://bbc.in/1lSW6Rl
People w/ “binge eating disorder..lower grey matter volumes..in OFC&striatum” which help keep track of goals/rewards: http://bit.ly/1ktGBDd
After eating – leptin travels up to #brain – reducing hunger – via astrocytes not just neurons: http://bit.ly/1rGQvpN
“mother’s high-fat diet triggers brain inflam in..developing fetus leading2anxiety&hyperactivity in offspring” [mice] http://fxn.ws/1C5UxNG
“trans fats increase the shelf life of foods..reduce the shelf life of people” +it makes you stupid: http://onforb.es/1xS2oZT
Another reason to stay in – Home cooking a main ingredient in healthier diet: http://www.sciencedaily.com/releases/2014/11/141117084711.htm
Obesity=chronic low-grade inflammatory state, influencing neuropsychiatric status thru’ effects of inflammation on brain (Castanon et al, 2014)
Cell hub within amygdala (renowned for it’s role in fear response) switches off urge to feed: http://bbc.in/1uy92G6 #neuroscience #brain
“Signals in the #brain that tell us to stop eating function less efficiently as we approach mid-life” http://bit.ly/1BdT8BD #thankyouHenry
Forget the gastric band, to reduce obesity we may some day just crank up the juice on our vagus nerve stimulator: http://bit.ly/1o65u9E
Weight gain/obesity from high fat/high sugar diet prevented when receptor is blocked – but where do the calories go? http://bit.ly/1uf9V2F
More mindless eating of high calorie food when brain area implicated in resisting impulses is experimentally zapped: http://bit.ly/1r7rtyv
Emotion
Doh, why did I do that? How could I be so stupid!! (Rat regret) http://bit.ly/1oGdPQE
Longest running study homes in on what really makes men happy: http://bit.ly/1jvAuME
“aggressive men’s blood pressure went down..non-aggressive men..blood pressure [rose,whilst watching violent scenes]” http://bit.ly/1uyW5Jf
“I’ve got a bad feeling about this” Habenula #brain region activated when viewing images assoc w/ nasty consequences http://bbc.in/1pzAATn
Changing flavour of a mouse’s emotional associations w/ a specific environment thru’ #optogenetic #brain stimulation: http://bbc.in/1qLM9Yl
“fine-grained patterns of neural activity w/in orbitofrontal…code that captures an individual’s subjective feeling” http://bit.ly/1wb9pSy
“Chewing gum, surprisingly, improved mood, possibly because chewing seems to increase blood flow to brain” http://bbc.in/1DANoAg
“What we have found is a process that may dampen the brain’s sensitivity to negative life events.” http://bit.ly/ZBYW9P
As days get shorter “production of a transporter protein ramps up in S.A.D., lowering available serotonin” http://bbc.in/1ye9RlH
Ever noticed that musclebound gym freaks seem particularly moody? Appears that stronger men are quicker to anger: http://bit.ly/1qvZE0Y
Exercise protects against depression – but how? – The rise of PGC-1a1 as a possible mechanism http://www.medicalnewstoday.com/articles/283057.php
Events
Today=Big Day. When that paralysed person kicks off the World Cup they’ll feel underfoot via their arm: http://bit.ly/1iqKGU4
#Brain play at Young Vic, London: “The Valley of Astonishment” until 12th July http://bit.ly/1peny3J
Fancy trying some EEG Pong? Just head down to the Royal Society’s Summer Exhibition starting 1st July http://bit.ly/1q9txWN
If anyone over there in the US lives near the Franklin Institute this Your Brain exhibition sounds ace! http://bit.ly/1xTJUc3
Birdies for brains – golfing 100 holes in 1 day to raise money for brain charity http://kare11.tv/1kY0Fh0
You’ve been quoted in my #Storify story “The App-othecary: Is the future of medicine calling?” http://sfy.co/a00Pk
#Today is #World #Brain #Day !! Love your brain http://www.wfneurology.org/world-brain-day#
If I was in Philadelphia right now I would go, immediately, to the Franklin Institute’s Neural Climb: http://bit.ly/1zA2ozO Sounds awesome!
Read ’em and sleep: how one tweet led to a literary lock-in http://gu.com/p/42nvn/tw via @guardian
Very much looking forward 2 speaking at the London Business Forum event with @polarbearpirate tomorrow morning: http://bit.ly/11iQKMr
The App-othecary: Is the future of medicine calling? is hosted by @DrJackLewis at @acmedsci on 18th in London http://www.eventbrite.co.uk/e/the-app-othecary-is-the-future-of-medicine-calling-tickets-13850500219
Evolution
Did #brains of pre-human ancestors thrive on bug diet / the challenge of making #tools to get at them? http://bit.ly/1qJPVDZ
Brawn v brain: During human evolution, the brain got stronger and our muscles weaker
Protective buttressing of the hominin face #sexualdimorphism #evolution
http://goo.gl/Eva1MU http://goo.gl/19SfmN
http://onlinelibrary.wiley.com/doi/10.1111/brv.12112/full
Did Standing Up Change Our Brains? http://neurosciencenews.com/bidepal-walking-cognitive-brain-change-1045
huh, interesting…Non-dominant hand vital to the evolution of the thumb http://bit.ly/1ulHl15
8,000 yr old (prob. human) brain found preserved in skull during archaeological dig in Norway: http://bit.ly/1nCc1si
Neanderthal trait found in archaic early human skull http://www.pasthorizonspr.com/index.php/archives/07/2014/neanderthal-trait-found-in-archaic-early-human-skull …
Film
Having been bored all week by Luc Besson’s Lucy inspired resurgence of articles on 10% #brain myth, this tickled me: http://bit.ly/1nB8NVD
Free Will
Free will emerges from brain “noise” http://bit.ly/1l2xbyo #neuroscience #EEG #freewill #noise #brain #SortYourBrainOut via @DrJackLewis
Funny
There comes a time in every neuroscientist’s life when the urge2make a human brain out of jelly becomes irresistibleX-ray GIFS of the human body in action http://bit.ly/1A4LrfB
Mathematical proof that hipsters all look alike http://wapo.st/1zk0otu
http://twitter.com/mocost/status/498756900956434432/photo/1pic.twitter.com/2ja2LbZ8rm
PNIS, it’s like The Onion for science: http://pnis.co/index.html
Gaming
Immersive virtual reality gaming is now so good it might be game over for reality, new blog just posted http://bit.ly/1lNOLYr
Video gaming in kids might not have adverse impact on cognition but “displacement threat” should not be trivialised http://bit.ly/1nKeKx9
Anyone want to make a game with me? http://www.tiga.org/repository/documents/editorfiles/onlinesubscribers/tiga_sources_of_finance_document.pdf
“Throw Trucks With Your Mind..ultra-violent meditative competitive game” – anyone? http://lat.ms/1oQ7HpM
Geek Chic
Nearly lunchtime (in Europe at least) Perfect opportunity to listen to ep1 of our brand new podcast!: http://bit.ly/1lwfx8E
New improved #GeekChicPodcast – out now!! Getting people hooked on healthy food, brain-to-brain comms & titanosaurs http://bit.ly/1qH2K2i
Saving lives with crisp packets, Xe memory erasers & @AsapSCIENCE animations on internet brains #geekchicpodcast ep4: http://bit.ly/1rinZJl
A True and Complete Account of the Neuroscience of Zombies – Scientific American http://ift.tt/1HeHLfT
Amazing Rosetta images show Philae bouncing 1km off comet: http://po.st/N8Im3Q by @jtemperton
New #GeekChic popscience podcast from me & @Xfm_Lliana. This week: pandas who fake it & lesbians who don’t need to http://tinyurl.com/mhvyt6x
Do we actually dream in slow motion? Find out in @DrJackLewis and my geek chic Podcast here: https://itun.es/gb/MYC82.c
Ever heard of coloured icebergs? Read about this natural phenomenon here: http://bit.ly/terranostra #travel #nature
#geekchicpodcast episode 4: http://bit.ly/1rinZJl
Cockroach biobots have caught the attention of the U.S. Department of Energy: http://bit.ly/1ui1Lbi
Geek Chic Science Weekly podcast will be available for download from today onwards #geekchicpodcast https://itun.es/gb/MYC82.c
Geek Chic Podcast Episode2 – Out Now!! How to get hooked on healthy food, vulcan-esque communication &huge dinosaurs: http://bit.ly/1qH2K2i
Geek Chic Weird Science Podcast is finally on iTunes!!! Pls download all episodes for FREE & share 🙂 x https://itunes.apple.com/gb/podcast/geek-chics-weird-science/id921816230?mt=2
Geek Chic Weird Science podcast, download, for free, from iTunes & listen anytime you like: https://itun.es/gb/MYC82.c
In Jan 2014 @Xfm_Lliana invited me2chat weird&wonderful science stories on XFM every Sun. Now we have a podcast! Ep1: http://bit.ly/1lwfx8E
Looking for some Fri distraction? #geekchicpodcast Ep3 Jack The Ripper Special -has science finally cracked the case? http://bit.ly/1qXEIBC
#geekchicweirdscience podcast ep9 Nobel Special is OUT NOW!! http://tinyurl.com/pw9w77a Catching up on new approaches to investigating Brain GPS
Abolishing arachnaphobia by taking a scalpel to the brain;very halloweeny article from New Scientist http://bit.ly/1089Cg7 @GCweirdscience
Anchoring the brain’s compass: http://bit.ly/1vzVYzV Little amuse bouche ahead of this week’s #geekchicweirdscience podcast @GCweirdscience
Curious about teleportation? Baffled by quantum entanglement? Prof Gisin explains all in our latest GCWS podcast: http://tinyurl.com/GCweirdscience
DidUcatch new ep of #geekchicweirdscience podcast? Killer whales speaking dolphin, transplanting sexual organs&more! http://tinyurl.com/pw9w77a
Geek Chic Weird Science ep10 – miracle spinal surgery, hoverboards, re-heated pasta, tractor beams & birds on Prozac: http://tinyurl.com/pw9w77a
Dolphins can detect magnetic fields and might well use this ability to help them navigate the oceans: http://bit.ly/1vbV1tO
Geek Chic Weird Science podcast ep7: “Teleportation Special” OUT NOW!! @Xfm_Lliana & I interview a quantum genius…
https://itunes.apple.com/gb/podcast/geek-chics-weird-science/id921816230?mt=2 … – ep6 – Out now! Cunningly cultured chimps, (potentially) calamitous comets & [gasp] a coffee crisis on the horizon
Rosetta Mission selfie http://wrd.cm/1wjGa3c
Thanks @DrJackLewis & @Xfm_Lliana for the fun interview abt the hippocampus, place cells & Nobel prize https://itun.es/i6B33FT
This one’s also very #geekchicweird science: http://echinoblog.blogspot.ca/2014/10/five-points-about-fossil-history-of.html
Being Halloween ’n’ all presumably someone out there fancies making a zombie..here’s a 1-stop-shop from @SciencePunk: http://amzn.to/1udf2V2
Bounce baby bounce: http://www.planetary.org/blogs/emily-lakdawalla/2014/11171502-rosetta-imaged-philae-during.html … #philae bounce data
Ever wondered how “homing” ravens in Game of Thrones reach their destination? Brain gyroscope+gravity detectors: http://bit.ly/1EG6iYQ
Geek Chic’s Weird Science podcast ep14 http://bit.ly/1rpMfIh Will we Clone Wooly Mammoths? Is Brain Electrocution better than Coffee? Et al
Spider brain, spider brain, does whatever a spider brain does… Delving into the jumping spider brain: http://nyti.ms/1yTGZQ7 @GCweirdscience
PODCAST: ep15 @GCweirdscience Do we dream in slow motion? Could you live a life aquatic? How to make a digital animal http://bit.ly/1rpMfIh
When Philae/Rosetta were first launched from French Guiana ten years ago..Twitter had yet to be invented via @RogerHighfield @GCweirdscience
“whales,dolphins&elephants share our ability2learn new vocalisations/3groups of birds:songbirds,parrots&hummingbirds” http://bit.ly/1AcRtdw
Print a personalised virus to kill your specific cancer and for a fraction of a price http://www.newscientist.com/article/mg22429990.200-i-want-to-print-personalised-cancer-drugs-in-a-day.html … – amazingly beautiful idea
Very Blade Runner, this: extracting images from corneal reflections http://ow.ly/GwUSZ
Lego robot with a worm brain: http://nydn.us/1ITmrgE OpenWorm project seems to be capturing imaginations all over the world @GCweirdscience
JanisCarter lived in cage onGambian river in effort2reintroduce domesticated chimp2wild: http://bit.ly/1B94mYi @Radiolab #SelfExpHeroes
New #GeekChic popscience podcast from me & @DrJackLewis. This week: pandas who fake it & lesbians who don’t need to http://tinyurl.com/mhvyt6x
PODCAST: we look back on the best weird science stories from 2014 in our 17th episode of @GCweirdscience http://bit.ly/1rpMfIh @Xfm_Lliana
Which is better: http://brainsciencepodcast.com/ or @GCweirdscience (paranormal science special will be released tomorrow!!) #battleofthepodcasts
No but seriously this is great – Swiss / Ukranian collaboration on homing pigeons, study required huge meteor crater: http://bit.ly/1EG6iYQ
Gut Bacteria
This account of human evolution sees us merely as puppets dangling on the strings of our gut bacterial puppeteers! http://theatln.tc/1mIVtAV
Balanced, well-written account of story-so-far re science taking influence of gut on brain more & more seriously: http://bit.ly/ZSBh5g
Nice update on the latest research investigating the link between gut bacteria and brain function from Nature http://bit.ly/1v5thvr #SYBO
“armies of bacteria living in our guts can pull the strings in our #brains to get what they want” http://onforb.es/1riA8jh #neuroscience #SYBO
Daily microbiome tracking – I wish I could have done this for my connectome!
Gut bacteria may influence food cravings2get what they want by sending message2 #brain via vagus nerve: http://bit.ly/1tLIhtA #weirdscience
Hallucination
How cultures influence content of hallucinations/delusions
Heuristics
Brains go to great lengths to preserve personal narratives -only getting labelled “confabulation” once at the extreme http://bit.ly/1nXJB8P
I don’t have a stock portfolio… but if I did I’d certainly keep these psychological biases in mind: http://onforb.es/1ou2oP6 #SortYourBrainOut
Attractive people are often assumed to be “good” but does being “good” bias people to rate them as more attractive? http://bit.ly/1rk7lEt
History
“Aldini zapped the #brain of a decapitated criminal by placing a metal wire into each ear & then flicking the switch” http://wrd.cm/1nUd5VT
Mosso machine 1882: get person balanced on plank, play them a sound, blood rushes to #brain, tipping the balance! http://n.pr/VzEyDu
Holding Onto Marbles
“Less time sitting down” = better way of helping older people keep their white matter in good nick: http://bit.ly/1ucWqQi #SortYourBrainOut
“cognitive health in old age reflects the long-term effects of healthy, engaged lifestyles” …but not “brain games” http://stanford.io/1rXY05B
Brain Age test for middle aged people to slam the brakes on our descent into cognitive decline – NICE! http://bit.ly/10OrbTA #RetirementDNA
Brain function can improve as you age: http://bit.ly/1yR3sgs – great to hear given that I’ve spent all day thinking about #RetirementDNA !!
I did a little piece in the Independent Online on Holding Onto Your Marbles to promote #SortYourBrainOut http://ind.pn/143Scnb #SYBO
You are what you..do for a living: http://yhoo.it/1ATx54x Daily mental activity induced by your job can help u build cognitive reserve #SYBO
The big message for #brain health to aid the battle against dementia in 2015? “Use It Or Lose It” http://ind.pn/1zN8dIY #SortYourBrainOut
“parts of the brain that were the last to develop were also the first to show signs of age-related decline” http://bbc.in/1ALZhX8
Intelligence
After decades of slowly increasing IQ it looks like we might now be going backwards. But why? http://bit.ly/1toL8JA #SortYourBrainOut
Outgamed by a chimp – in your face Homo sapiens! http://bit.ly/1nSsRj4
Interview
What Entrepreneurs Can Learn From Neuroscience w/ @DrJackLewis
Language
Time to learn a new language? “those who spoke2or more languages had significantly better cognitive abilities” http://bbc.in/1tAAZYi
“Listening effort and accented speech”. http://feedly.com/e/Scjtk42b The case for NOT outsourcing call centers?
This is unbelievably amazingly awesome – Star-Trek style instant voice translation
“people who speak more than 1 language fluently have better memories..more cognitively creative & mentally flexible” http://bit.ly/1rODTNM
If you get someone to say a word out loud, but tweak the sound of their own voice, you can make them talk nonsense: http://bit.ly/1xEGBT1
Mandarin speaking nanny for your infant child,perhaps? Adult brains recognise language features from infancy exposure: http://ti.me/1zDi8jV
Learning
“..striatum learns the pieces of the puzzle and then the prefrontal cortex puts the pieces.. together.” http://bit.ly/1lUHip6 via @PsyBlog
What goes on inside the brain as we learn from our mistakes http://ti.me/1qBjfwJ
Don’t Dismiss MOOCs – We’re Just Starting To Understand Their True Value: http://www.science20.com/the_conversation/dont_dismiss_moocs_we_are_just_starting_to_understand_their_true_value-144160
Dopamine helps with math rules as well as mood: http://www.sciencedaily.com/releases/2014/12/141205093831.htm
Utilise the “dead time”: Essential health info,distilled into small chunks,offered not force fed -perfect!
Meditation
Laughter puts #brain in2state similar to that of deep meditation
Memory
Nice short video with distinguished neuroscientists explaining basics of #memory: http://bit.ly/1nuJPcC
Bring unpleasant memory to mind, inhale Xenon, goodbye emotional pain – future of recovery from heartbreak / trauma? http://bit.ly/1rinZJl
Incredibly intricate interplay between hippocampus and septum enables us to create chunks of memory: http://stanford.io/1qct5GK #neuroscience
Default mode network, usually associated with daydreaming/mindwandering, very much involved in certain memory tasks: http://bit.ly/1sh2Hrk
Obama dishes out: $810k MIT – determining which exact brain circuits are involved in generating short-term memories that influence decisions
fMRI: CA3 overlap in #hippocampus may explain when we find it “difficult2differentiate between similar past memories” http://bbc.in/1mfkjGb
“frontoparietal network plays key role in analysis,memory retrieval,abstract thinking&problem-solving/fluidity2adapt” http://bit.ly/1A8dEBm
NEWSFLASH: memory may not be in synapses http://bit.ly/1DUXmSH Next they’ll say action potentials are just there 2 generate electric fields
On the topic of TMS.. 20mins of daily magnetic stimulation for just 5 days improved memory in study of 16 volunteers: http://bit.ly/1qlNN5w
Shedding New Light on the Formation of Emotional Fear Memories: http://neurosciencenews.com/memory-formation-hebbian-plasticity-1605/ #neuroscience #memory
Mind Over Matter
Cool! RT @mrianleslie: This is amazing: the neuroscience behind Bruce Lee’s “one-inch punch” http://www.popularmechanics.com/science/health/nueroscience/the-science-of-bruce-lees-one-inch-punch-16814527
Mind over matter – Wim Hof can withstand freezing swims/hikes in bare skin – 3 tricks to control his body & #brain: http://bit.ly/VQBVNS
These incredible robot exoskeletons used in Korean shipyards remind us of something… More: http://ow.ly/zVJ54
Morality
Possible neurobiological basis for tradeoff between honesty and self-interest http://www.sciencedaily.com/releases/2014/09/140902114230.htm
Morality pills: reality or science fiction? http://www.theguardian.com/science/head-quarters/2014/jun/03/morality-pills-reality-or-science-fiction
Music
Musical training improves various aspects of executive #brain function in old & young alike http://bit.ly/1p9jaCR
Speaking of Default Mode Network: activity ramps up when you hear song you like -is this losing yourself in the tune? http://huff.to/XvXxQA
Numerous benefits of providing music lessons to underprivileged kids includes improved language processing http://n.pr/1nMzbZL
Music saved my voice: http://bit.ly/1v0ApGZ Brain aneurysm robs music teacher of ability to speak, melodic intonation therapy wins it back
Been wondering when a band would jump on the binaural beat bandwagon – headphones on – relaxing?: http://bit.ly/1k9Dcv8 #SortYourBrainOut
What Wired thinks about a music neuroscience app that helps you increase focus by many hundred % http://wrd.cm/1j8VSu9 #neuroscience #music
Why is melody in the high notes and rhythm in the bass: http://bit.ly/1A5RsJO #neuroscience #music #SortYourBrainOut #SYBO
Navigation
Fascinating research from @hugospiers throws more light on #brain navigation systems http://bit.ly/1nWhMTx
Bat Nav http://bbc.in/124L3lb @GCweirdscience
Your brain’s internal compass – the stronger the signal it produces, the better your sense of direction: http://bbc.in/1r5IY48 @hugospiers
Neuroanatomy
If your brain was size of planet Earth..this infographic shows size of its nuts&bolts http://bit.ly/1jUrCTq
The Neuromythology of Einstein’s Brain http://blogs.discovermagazine.com/neuroskeptic/2014/05/24/myth-einsteins-brain/
Leonardo Da Vinci with his neuroscientist hat on: http://bit.ly/1Afvwfz #neuroscience
If I get hold of a cow brain would anyone be interested in bringing their kids2see a live dissection? http://bit.ly/1yjsFTz @GCweirdscience
Convention Defying Brain Cell: new neuronal “short-circuiting” feature spotted in brain’s memory bank: http://bit.ly/ZknTqq
Brain’s glial cells – long thought2be *just* passive support cells – increasingly recognised to play important roles: http://bit.ly/1qwK2Y5
Prodding around inside human brains during neuroanatomy practicals I always wondered what the choroid plexus was for: http://bit.ly/1rF1LQL
From physics to neuroscience: “Single neurons, he said, are fairly well understood, as are small circuits of neurons” http://nyti.ms/1xq0gbL
Bizarre Human Brain With No Wrinkles Discovered http://www.iflscience.com/brain/lost-and-found-smooth-human-brain
Major brain pathway rediscovered http://gu.com/p/43cmm/stw
100 missing brains: http://bit.ly/1zmmRpD If you are entrusted with Einstein’s brain you really should take more care.. @GCweirdscience
Regions of the brain strengthen with age http://medx.cc/334222167 #neuroscience
Astrocytes:always the bridesmaid,never the bride in discussions about #brain function;’til now? http://bit.ly/1qKqxBt #neuroscience #memory
Investigating factors that cause the #brain surface to fold up forming the distinctive peaks & valleys: http://bit.ly/1o9ih6A #neuroscience
Neurodevelopment
Ultra-fine particles found in air pollution seem to play havoc with early brain development
Consumption of highly-sweetened drinks throughout adolescence leads to cognitive impairment (in rats, so far) http://bit.ly/1s4q0rm
Great advice re: how best to stretch a child’s #brain described at 3m40s in this lovely interview: http://bit.ly/1mDK2r6 #SortYourBrainOut
Baby’s brain rehearse speech five months before they talk http://bit.ly/1ne4HUC @ScienceDaily #babytalk #SYKBO via @perked_brain
“..newborn #brains grew at an average rate of 1%/day” Cerebellum doubles in size over 1st 90days http://bbc.in/1pMeC2q #neuroscience #SYKBO
“When it comes to #brain development, time in the classroom may be less important than time on the playground” http://n.pr/1p9PMdK #SYKBO
On topic of importance of play4children.. Nils Norman compared adventure playgrounds across globe, book only £85!!: http://amzn.to/1oqSlDh
The Case for Packing Libraries Full of Toys and Games – http://www.citylab.com/work/2014/08/the-case-for-packing-libraries-full-of-toys-and-games/375530/ … #creativity
Young humans grow up much slower than our primate cousins because our #brain is so “energy expensive”: http://bit.ly/1p9Jpsb #neuroscience
Neuromarketing
Interesting thoughts on using insights from neuroscience in #advertising / #marketing: http://bit.ly/1pZqMIt via @stromilof #neuroformed
So good it needed tweeting twice: http://bit.ly/1rR9oCr Shared brain activity in few predicts audience preferences at large #neuroformed
Happy shoppers come in many varieties: run-of-the-mill happy, happy-excited. happy-aroused & (beware) happy-frenzied! http://n.pr/11vQjxY
Neuromyths
Neuromyths are hampering education
Christian Jarrett is worried about the impact of neuromyths on society
Exploding the 10k hrs of deliberate practice #myth – it’s no guarantee for greatness
Beware fake brain science in schools: http://slate.me/1yjtsEg
Neuroplasticity
NHS Choices continue to marshal the dubious fringes of science journalism – multi-tasking shrinks your brain, huh? http://bit.ly/1CrolB3
“30mins..daily training for 1 month..improvement in..ability to understand speech in noisy..conditions” http://bit.ly/1pAFh20
This is the most accurate description of our study: Media multitasking ‘brain shrink’ claims unproven NHS Choices – http://www.nhs.uk/news/2014/09September/Pages/Claims-media-multitasking-shrinks-brain-unproven.aspx
Bats are the only creature that can see using echolocation, right? Wrong! This amazing young blind lad can do it too: http://youtu.be/TeFRkAYb1uk
Brain Scans Reveal Gray Matter Differences in Media Multitaskers: http://neurosciencenews.com/gray-matter-acc-multitasking-1358/ … #neuroscience
Brainy processing at your fingertips http://gu.com/p/4xbpk/tw #neuroscience
Football “is a triumphant display of the incredible plasticity of the human brain http://bit.ly/1lkr3RP
How Culture Shapes Our Senses – NYT http://nyti.ms/1oUsT9S @tanyaluhrmann Ht @somatosphere
Making it to 24 years old without realising your whole cerebellum is missing is a true testament to neuroplasticity: http://bit.ly/1rXP3ja
My PhD supervisor used2say painters were visual scientists. Here @wiredscience effectively suggests same4film editors http://wrd.cm/1pMHIS0
When it comes to changes in brain thickness… Bigger is not always better: http://wrd.cm/1taWfr8 #geekchicweirdscience @GCweirdscience
Coaxing brain support cells (glia) to convert into electrical brain wires (neurons) to fix damaged parts of the brain http://bit.ly/1yY0aYd
Zoe Kourtzi leads Adaptive Brain Computations project in Cambridge; aiming to understand & test how learning happens: http://bit.ly/1t9XoM8
“Vagus nerve stimulation takes advantage of the brain’s neuroplasticity” to cure tinnitus: http://bit.ly/1rcV1bm #neuroscience #tinnitus
Well read? How digital reading is changing (hurting) comprehension. http://www.newyorker.com/online/blogs/mariakonnikova/2014/07/being-a-better-online-reader.html
Intensive smartphone use causes your brain’s territory for processing thumb sensations2enlarge: http://fxn.ws/1xqnpOz 169articles in 4days!
Neuroplasticity in action – how your touch screen devices are changing your brain: http://bbc.in/1zTWzvY #SortYourBrainOut @polarbearpirate
The Tortured Brain – Insightful article that pulls together info on CIA torture practices, neuroplasticity & PTSD: http://bit.ly/1whLEax
Something special about neuronal gamma activity (40Hz)-making mouse #brain supersensitive2gentle touch: http://bit.ly/1pvFLIk #neuroscience
Sleep-Dependent Neuroplastic Changes during Auditory Perceptual Learning http://www.sciencedirect.com/science/article/pii/S1074742714002111
Neuroscientists
If I was Miguel Nicolelis I’d B getting really nervous about 2morro’s brain-controlled exoskeleton world cup kick off http://bit.ly/1kKhxI6
Here’s a short film I edited & animated of interviews with top scientists at last year’s BNA conference http://bit.ly/1mNF2hl
Here’s a taste of 10 interviews I filmed w/ top neuroscientists at the British Neuroscience Association conference http://bit.ly/1mNF2hl
Trouble at t’mill: KCL scientists facing mass redundancy. Sounds brutal. My heart goes out… http://bit.ly/T32nlT
Did I mention I interviewed some of world’s top neuroscientists &cut a short animated film? 🙂 http://bitly.com/1mNF2hm
On subject of @hugospiers, here he describes role of #hippocampus in imagining future scenarios http://bitly.com/1mNF2hm
How to Criticize with Kindness: Daniel Dennett on the 4 Steps to Arguing Intelligently http://www.brainpickings.org/index.php/2014/03/28/daniel-dennett-rapoport-rules-criticism/ … via @timetit
Nice interview with Charles Spence in CB. Even manages to diss post-pub peer review on the way 🙂 http://www.sciencedirect.com/science/article/pii/S096098221400387X
Charles Limb – head & neck surgeon, improv pianist & rapper exploring brain mechanisms of creativity: http://bit.ly/ZMAAKo @GCweirdscience
Future of the Brain, anyone? Collection of essays from some of the world’s leading thinkers in neuroscience: http://bit.ly/1DGxTMy
Coming soon ‘The Para-Academic Handbook’ http://hammeronpress.net/page19.htm <you don’t have to be in academia to do good research or innovative practice
Meet the mother and father of cognitive neuroscience @utafrith & @cdfrith | @mocost http://gu.com/p/4x56x/tw via @guardian
Fascinating article: http://bit.ly/1vblwDw by @hugospiers – who we interviewed for next week’s #geekchicweirdscience Nobel Special podcast
John O’Keefe is a living legend anyway & now his scientific genius has been recognised with a Nobel prize! http://tinyurl.com/johnokeefenobel #brainGPS
My favorite professor of behavioral economics, @danariely recommends MOOC by @paulbloomatyale, so I’ll be tuning in. http://ow.ly/C8DcK
One of my favourite personalities in #neuroscience defending Europe’s Human Brain Project from a broadside attack: http://bit.ly/1t3imgF
Neurosurgery
Successful trepanation on Mongolia/China border 2,300 years ago – what was the motive for this hole-in-head surgery? http://dailym.ai/1p2g7XI
Genius! Neurosurgeon predicts diagnosis of brain area impacted by stroke – asking patient to speak a 5 word sentence: http://n.pr/1mG9COM
Fantastic description of how surgical treatment of epilepsy helps us do phenomenal #brain research: http://nyti.ms/1kDsAz2 #SortYourBrainOut
Can’t get enough of the concept of playing the violin whilst surgeons operate on your #brain: http://cnet.co/1tjWnCd #neuroscience #SYBO
The Fascinating Reason This Man Is Playing Violin During His Own Brain Surgery by @erbrod http://mic.cm/1sRlj5s via @MicNews
Optical Illusions
Here You can change some visual attributes to increase or decrease the café wall illusion. http://joyfulcoder.net/cafewall/
This is definitely one for @GCweirdscience Spinning chocolate cake illusion: http://youtu.be/HxSN1FkcZ64 Stunning #GeekChicWeirdScience
Optical illusions anyone? Go on, you know you wanna spend your lunch break tying your occipital lobe in knots: http://wrd.cm/1vlRIV1
Other Creatures’ Brains
Devil rays have “sponge-like mesh of large&small arteries” to warm their #brains during 2km deep dives http://bbc.in/1qR5fyV #neuroscience
39,000 year old Wooly Mammoth brain (with a well preserved “tough mother”): http://bit.ly/1sscZVX @GCweirdscience
“humble nematode worm has..its neural connections hot-wired,changing the way it responds 2 salt&smells” http://bit.ly/1rcXJxt #neuroscience
Elephant’s nose best: African elephants have twice as many olfactory genes as any other mammal. http://feedly.com/e/r_rCUv8d
Giant prawn fossil discovered in China has perfectly preserved 520Million year old #brain: http://bit.ly/1nO2f6m #archaeology #neuroscience
RT @mocost: 80,000 neurons firing in zebrafish http://bit.ly/UIaXHv http://wrd.cm/1qaCTOg http://bit.ly/UIaXHw
Dolphins & Beluga whales squeal with delight when they know a prize is coming their way: http://bit.ly/1twlbbV #brain #reward #weirdscience
Lethal aggression in Chimpanzees is better explained by adaptive strategies rather than human impacts http://www.nature.com/nature/journal/v513/n7518/full/nature13727.html
If crayfish can convert blood cells2brain cells2replace damaged ones-why cant we? http://bit.ly/1nLlKYV #neuroscience #transdifferentiation
In other news today, scientists have taught fish how to walk http://bit.ly/1qDaoM9 http://youtu.be/mKxRe0hAQmg?list=UU7c8mE90qCtu11z47U0KErg
Pain
Swearing when you hurt yourself actually makes it feel better. http://DiscoverMagazine.com Cursing & #hypoalgesia.
Chronic back pain? Maybe it’s time to quit smoking http://bit.ly/1s1vu3d I find the explanation hard to believe; make of it what you will !
The benefits of psychological treatment for chronic back pain http://blog.backpainrelief.net/the-benefits-of-psychological-treatment-for-chr
Parenting
Fascinating! Gay dad #brain responds to new parenting role (adoption) just like both straight parents: http://ti.me/1jWeNbd
Many pregnant women are slightly iodine deficient which can have knock on effect on their baby’s #brain development: http://bit.ly/1k952k6
Supportive parenting is neuroprotective: http://bit.ly/1pGUuxm
Amazingly, fatherhood actually changes a man’s #brain: http://wrd.cm/1qKEoDw #neuroplasticity #neuroscience #SortYourBrainOut #SYBO
For those archaic types that still believe a good spanking is good for your kids – not true, read this: http://cnn.it/1x0ORN7 #neuroscience
As women leave childbirth later,will this: http://tinyurl.com/pptt85y (mitochondrial problems) lead 2 more of this? http://tinyurl.com/nh73ek6 (IVF)
Personality
What is introversion? What REALLY defines an introvert? Or an extravert for that matter http://bit.ly/1oJ0qaw
Why The Myers-Briggs Personality Test Is Misleading, Inaccurate, And Unscientific via @bi_strategy http://www.businessinsider.com/myers-briggs-personality-test-is-misleading-2014-6
Pornography
Negative correlation discovered between pornography consumption&volume of striatum (drive, reward etc) #neuroscience http://reut.rs/1tT54Ej
“increasing numbers of young men…cannot maintain an erection because they’ve wrecked their appetite w/ pornography” http://bbc.in/1jlZ8lW
Pornography ” is an addictive, disruptive drug in visual form.” http://ow.ly/FbTqM h/t @EduardoZugasti
Poverty
Poverty can be so cognitively demanding – little mental energy left for anything else
Psychology
Sports psychology perspectives on Luis Suarez’s propensity to bite people http://bit.ly/VqvGB9
Nice example of using knowledge of the #brain to underpin habits of thinking that help you get what you want http://www.huffingtonpost.com/2014/06/07/brain-science-get-what-you-want_n_5455366.html?ir=Healthy+Living
Psychology is weird, child psychology is much weirder. http://www.slate.com/articles/health_and_science/science/2014/06/developmental_psychology_s_weird_problem_children_from_rich_educated_families.html By @jane_c_hu via @le_feufollet
Quotes
“Science does not know it’s debt to imagination”
“There is a road from eye to heart that does not go through the intellect” #SortYourBrainOut
Levi Roots’ reggae reggae message: Be yourself Believe in yourself If you fail in 1 passion – merge it with another 1
“I have decided to be #happy, because it’s good for my health.” -Voltaire
“ If you were a plant…you would think of a drug as this: ‘Something I use to make animals do what I want’ ” @zoecormier SexDrugsRock (2014)
“Any fool can know. The point is to understand” ― Albert Einstein
If you don’t know where you are going, any path will get you there. ~ Lewis Carroll
“Every man can, if he so desires, become the sculptor of his own brain” – Santiago Ramón y Cajal
“The hardest thing to learn in life is which bridge to cross and which to burn” ― Bertrand Russell
Religion
Bit of light Fri reading on “Neurotheology – neurological study of religious & spiritual experiences”
Reviews
Wow – that’s 3/3 book reviews so far suggesting Susan Greenfield’s new book is more “Mind Cringe” than “Mind Change”: http://econ.st/1thls49
1st thought: ‘TV series called “Hack My Brain” – why didn’t I think of that?’ then I actually read the review – Ouch! http://nyti.ms/1saEZ6B
Reward Pathways
“the striatum shows more activity to monetary rewards when the reward was judged to be fair” http://bit.ly/1sGyh5x #SortYourBrainOut
Doing it with someone else makes it feel more intense: http://tinyurl.com/Do1tTogether …whatever “it” may be!
How to create an addictive gaming experience? Hijack the reward system. Unfortunately, it really is as easy as this.. http://n.pr/1oUcljA
Study investigating curiosity highlights the importance of dopamine in learning… not just pleasure and drive: http://bit.ly/1vyhlyk
Stimulation of the “pleasure hub” (VTA) whilst mouse dreams of a certain place in space makes it prefer it when awake http://n.pr/1BQwDp6
Science Communication
Learning about #science through #comedy: http://bit.ly/1uWMiju
Loving animations like this that illustrate our #brains in action..even with the inevitable corner-cutting: http://bit.ly/1cKa7An #SYBO
This truly is a thing of beauty: http://bit.ly/1pLYoUe Immaculate narrated-animation depicting 2000yrs of human migration via @tomstafford
Senses
“Stem cells in the tongue produce new taste cells every fortnight” http://bbc.in/1xbDiY2
Olfactory Reveille: it’s now possible to purchase an alarm clock that emits the smell of bacon at “wakey-wakey” time! http://bit.ly/1BxT0MK
New study: Neurons in your skin perform advanced calculations http://ow.ly/3pNMcr
Newsweek Interview: Digitising Smell: The Third Sense Is Coming to Your Phone – interview with @adriancheok http://www.newsweek.com/2014/09/19/digitising-humanity-about-take-another-huge-step-forward-smell-269729.html
Every cloud… silver lining of #dyslexia is a #brain that is more adept at certain visual abilities: http://bit.ly/1z4IQQq #neuroscience
Reaching for object of unknown size in cluttered environment people grasp correctly anyway – spooky! http://bit.ly/1GHHmiV @GCweirdscience
Bee brains – with only a million neurons (we have 86 Bn!) – can still see the big picture: http://bit.ly/1w4zKp8
Cunning study: how brain makes vision feel Hi-Def despite fovea only covering area size of thumbnail at arm’s length: http://bit.ly/1waUDxo
Why we don’t (usually) notice stunt doubles: http://bit.ly/1sQle3S Brain design “feature” not “flaw” #SYBO #SortYouBrainOut @GCweirdscience
Can humans really distinguish 1 trillion different odours? Or just 10? http://arxiv.org/abs/1411.0165 via @ewencallaway
Neuroscience of Taste: Chef’s Creations Delight the Senses – Live Science http://ift.tt/1EZ3PJs
It’s beginning to smell a lot like Christmas: The neuroscience of our nostalgia. http://ow.ly/GplSt #science
The taste of music – courtesy of the crown prince of multisensory interactions: Prof Charles Spence http://bit.ly/1yz5H69 #SortYourBrainOut
If it was 1st April there’s no way I would post this – ‘average’ person can guess ur car from ur face: http://bit.ly/1tLDzfl #weirdscience
How #brain sees shape that isn’t really there. Less activity required when illusory contours perceived http://bit.ly/1sR6QZw
Insights into vision from people blind from birth but given back the gift of sight in adulthood by science/medicine: http://nyr.kr/1qkNeZT
Where Hollywood movies and #neuroscience converge: http://wrd.cm/YWb1WU #brain #vision
Sex
How I Rebuilt Tinder And Discovered The Shameful Secret Of Attraction http://www.buzzfeed.com/annehelenpetersen/we-are-all-classists?bffb&utm_term=4ldqpgp#18dhj72 … oh, this is quite interesting!
Easy Access Internet Porn: “..worries &frightens people..creates anxieties about their bodies &sexual performance…” http://bit.ly/1xtwqVZ
The headline we’ve all been waiting for: Sex is good for your brain http://huff.to/1neOpMc … it was only a matter of time
Lesbians have more orgasms than straight women – so should straight men ask lesbian friends 4 some tips? http://bit.ly/1vFhK2k #sexhospital
Showreel
I’ve compiled clips from TV series I’ve presented http://bitly.com/1u10k21 Please watch&let me know which clips are best #crowdsourcedshowreel
Thank you @jjunno for your selections: “TM05-SH04-HT01 and you had at HT 03 :)” #crowdsourcedshowreel
Using Wisdom of Crowds to make perfect showreel, pls pick favourite clips: http://bit.ly/1u10k20 #neuroscience #brain #crowdsourcedshowreel
Sleep
“Working antisocial hours can prematurely age the brain&dull intellectual ability” #SortYourBrainOut – get a new job? http://bbc.in/1x28EyH
Not just too little (<6hrs) but also too much (>8hrs) sleep is linked2poorer cognitive function in older people http://bit.ly/1rFrgjK
“The less older adults sleep, the faster their brains age” http://bit.ly/1sTSrvQ
ASMR for #insomnia? Soothing/tingling sensation travels over scalp in response2specific types of sensory stimulation http://nyti.ms/1tyjv2T
I often bang on about importance of good night sleep 4 #brain health -so it’s good to see evidence accumulating http://reut.rs/TcTHKv
Lack of sleep linked to negative thinking http://bit.ly/1vzjM1t (and neurodegeneration http://bit.ly/1lnf07j)
Doesn’t surprise me one little bit: http://m.bbc.co.uk/news/health-29166466 … I often find myself continuing daytime tasks in my sleep (even debugging code!)
Earlier I admitted2solving computer programming bugs in my sleep.According2 @sciammind it’s been going on since 60’s! http://bit.ly/1oBHTtY
Implanting designer gene into certain region of brainstem makes deep sleep switch-on-and-offable: http://bit.ly/1s6gE1T
In #SortYourBrainOut @polarbearpirate & I stress importance of sleep for brain health,here’s why + ways2improve sleep http://bit.ly/1BdicI6
It’s not big, it’s not clever… going without sleep is deleterious to brain function: http://theatln.tc/1wfaM7n #SortYourBrainOut #SYBO
Love how cunning yet simple this experiment is: http://bbc.in/1r9SN1a – establishing whether or not we dream in slow motion via @BBC_Future
To Sleep, Perchance To Learn: why memory suffers when we’re sleep deprived & the chemical injection that can boost it http://n.pr/1BQwDp6
“#memory distortion is greater after #sleep deprivation..people are getting less sleep each night than..ever” http://bit.ly/1ne7M68 #SYBO
#Meditate While Lying in Bed For More Restful #Sleep http://ow.ly/Gebe6 #SortYourBrainOut
Get a new iPad for Christmas? Don’t use it just before bedtime or it will screw up your sleep: http://bit.ly/1xrLuEA #SortYourBrainOut
‘Sleep drunkenness’ more common than thought, new study finds – Health – http://TODAY.com http://ow.ly/AMb6q
The chicken and egg of sleep problems / beta amyloid deposition in the brain of elderly people: http://bit.ly/1vzkuf8 #SortYourBrainOut
Why we yawn: http://bit.ly/1H7se0c @GCweirdscience @Xfm_Lliana #behindthepaywall
Stress
#Stress, can provide benefits IF you don’t let it hang around too long | p129 http://ow.ly/AIcqk @drJackLewis
How #stress hormones promote #brain’s building of negative memories (@ScienceDaily) http://bit.ly/UvhoO2 #trauma
Impact of stress on body and #brain is a core part of #SortYourBrainOut philosophy. Brilliantly described here: http://n.pr/UdECbJ #SYBO
Talks
Last week i did a talk on #bodylanguage @MiddlesexUni & promised i’d write a blog up about it. I’m a man of my word: http://bit.ly/1mzlKw9
Confirmed panellists for “The future of self-hacking”: @DrJackLewis, @StuartCalimport, and Andrew Vladimirov http://www.meetup.com/London-Futurists/events/190686472/
TVInsight into how NatGeo decides what kind of series to fund – stumble on something that works, copy it: http://fxn.ws/1oNHHKp #scienceTV
Could viewers hear me mutter, under my breath, right at the end: “ethically dubious.. but lovely” – I wonder? #ThisMorning #miniWinnie
Virtual Reality
Fascinating! People more comfortable sharing secrets w/ #virtual human (computer controlled) than real 1 http://bit.ly/1oFjCCT #psychiatry
Window to the Soul
“pupil dilation correlated more closely with perceived effort than actual effort” – for both physical & mental effort http://bit.ly/1udmkWt
Catching undiagnosed glaucoma before it damages vision – simply by analysing eye movements whilst people watch telly: http://bit.ly/110f99a
Young Brains
In low-income neighborhoods, 1 book is available for every 300 kids. In richer areas the ratio is 13 books per child http://anniemurphypaul.com/2014/06/why-pediatricians-are-prescribing-books
What’s Lost as Handwriting Fades: http://nyti.ms/1kqAhfj
What happens in a teenager’s brain when they are criticised by their mother (what it means is another matter) http://wrd.cm/1uOM5by #SYKBO
Analysis of 5-HT receptors in brainstems of babies who died of SIDS (a.k.a. cot death) reveal new subtypes/functions: http://bit.ly/16IzIKo
A Vaccine for Childhood Anxiety: Effort-Based Praise http://ift.tt/1rUTZTK #psychology
Baby brains – how you curate their environments & choreograph their social interactions sculpts their personality: http://huff.to/1xz0O21
Newborns spend about 16-17 hours sleeping a day. But about 80% of neonatal and newborn sleep time is actually REM (‘dreaming’) sleep.
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Hang Onto Your Marbles by Dr Jack Lewis
No comments yetPosted in Aging BrainsJul 31, 2013
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As we progress through life we inevitably find ourselves becoming increasingly forgetful. It is not as if bouts of forgetfulness never occurred when we were younger. It’s just that it begins to happen more and more frequently – to the point where it becomes much more noticeable; even troublesome . From our mid-twenties onwards we lose more neurons (brain wires) and synapses (connections between the brain wires) than we build. The long term end point of this perfectly natural, gradual process of brain aging is dementia. By which I mean if we all lived to the impossibly grand old age of 200, every single one of us would have developed dementia of one description or another along the way. In reality very few of us will even make it to the grand old age of 100, let alone 200. Of those that do, not everyone will have become plunged into the amnesic fog of dementia. So what is the difference between individuals that do and don’t develop dementia well into their senior years? Is it blind luck? Or is there something we can do to lengthen our dementia-free status? -
Might New Arthritis Drugs Delay Dementia As Side Effect?
1 Comment »Posted in Aging BrainsAug 23, 2011
Read more »COLUMBO’S DEMISE FLAGS MECHANISM FOR ACCELERATED DEMENTIA
Columbo, played by Peter Falk, suffered with severe dementia for several years before he died in 2011 aged 83
A recent article in the Daily Mail described how Peter Falk, the actor who played Lieutenant Columbo in the famous 70’s detective series by the same name, rapidly declined from mild into severe dementia in just one year. In early 2007 he was acting in a feature film, but by the end of that same year, after a series of dental operations, his daughter was in court filing for legal guardianship of her father because he could no longer recognise familiar people, places or objects. Such tragic stories inspired recently published research investigating possible links between acceleration of progression from mild to severe dementia and seemingly unrelated health problems.
Professor Clive Holmes and colleagues at the University of Southampton published a paper in last month’s Neurology journal, which may provide an explanation for the mighty Columbo’s rapid descent into severe dementia. They monitored a group of 300 people with dementia over 6 months and found that, when certain elements of the immune system were mobilised, the incidence of certain neuropsychiatric symptoms doubled. This may suggest that Peter Falk’s rapid decline into severe dementia may have been caused not by the series of dental operations per se, but rather his immune system’s response to those operations. Professor Holmes’s investigation observed elevated concentrations of tumour necrosis factor (TNF), amongst others, in individuals whose dementia-related “sickness behaviour” worsened during the 6 month monitoring period.
TUMOUR NECROSIS FACTOR – double-edged sword
TNF is involved in the inflammatory response to tissue damage and its major role is to regulate the function of immune cells. TNF is also something of a grim reaper as far as cells in our bodies are concerned, as it can induce apopotosis – programmed cell death. Apoptosis might sound like a bad idea but it is actually very important for cells to have a self-destruct button, otherwise removal of malfunctioning cells would be impossible. TNF is a natural component of our immune system that kills off, amongst other things, dangerous damaged cells that start to multiply out of control i.e cancerous tumour cells: Tumour – cancer; Necrosis – killing; Factor – agent. So, when you see TNF, think “Cancer Killing Agent.” However in a person with Alzheimer’s disease, whose brain cells are being increasingly clogged up with neurofibrillary tangles and stuck together with the accumulating amyloid plaques, it seems that high levels of TNF make matters worse by accelerating the onset of severe dementia.HALTING DEMENTIA with ARTHRITIS DRUGS?
TNF has long been implicated in autoimmune illnesses such as rheumatoid arthritis. Many drug companies have invested vast sums of money in order to bringing anti-TNF drugs to market as an effective treatment for rheumatoid arthritis. Many severely arthritic individuals across the globe are currently enjoying significantly improved quality of life as a result of using such “biologics” to reduce the swollen joints that often leave people with terrible pain and significantly reduced mobility. But that’s not all. Recent studies have revealed that TNF plays a significant role in the development of Alzheimer’s disease and that treatment with anti-TNF drugs can improve dementia symptoms considerably. Indeed, more than 10 years ago a Danish study revealed that levels of TNF in elderly people were elevated and that TNF levels were positively correlated with dementia. An American study came to a similar conclusion. But of course back then these marvellous anti-TNF drugs hadn’t yet hit the market.
Unfortunately the anti-TNF drugs currently taken by individuals with arthritis are largely ineffective in combating dementia. This is because they simply cannot get from the blood stream into the brain (unless they are injected directly into the spine.) This is because the Blood Brain Barrier (BBB), which wraps around every blood vessel that passes through the brain, tightly regulates which molecules are allowed into the brain. Large molecules like these dementia-smashing anti-TNFs are most definitely “not on the list” so although there are many elderly arthritis sufferers with plenty of the good stuff sloshing around in their blood stream, it simply can’t get into the party. In their current form these drugs are unlikely to play a significant role in keeping dementia at bay given how impractical, not to mention dangerous (given the infection risk), repeated spinal injections are.TROJAN HORSE TO THE RESCUE?
Anti-TNF compounds riding Trojan horses may one day help to delay the onset of Alzheimer’s disease for us all
Brand new drug technologies can however attach therapeutic compounds to naturally-occuring molecules that are on the BBB list – a so-called “molecular Trojan horse.” Special transporter proteins embedded in the BBB “recognise” the shape of the naturally-occuring molecule as friend rather than foe, allowing it to attach to the transporter protein and be pulled, along with the attached anti-TNF compound, inside the brain. Once drug companies have managed to create anti-TNF Trojan molecules, acceleration of dementia can be prevented by suppressing TNF activity in the brain. In the not too distant future, we might all soon find ourselves keeping Alzheimer’s at bay with anti-TNF drugs that ride Trojan horses to the rescue by defending our brains from the perils of TNF “friendly fire.”
In addition to these weekly brainposts you can also catch Dr Jack’s daily #braintweet by following him on Twitter.
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Cognitive Reserve Keeps Alzheimer’s Dementia at Bay by Dr Jack Lewis
2 Comments »Posted in Aging BrainsJul 14, 2011
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Elderly people who do not suffer with Alzheimer's tend to exercise regularly, eat healthily, seek mental stimulation, are proactively engaged in a varied social life and are well integrated into their community. These lifestyle choices do not guarantee to keep dementia at bay, but it sure as hell can't hurt to try
Contrast the lifestyles of people in their seventies who do and do not suffer from Alzheimer’s disease and clues about how to keep your brain ticking over nicely, well into old age, jump right out at you. Those who do not suffer with this dreaded disease tend to have been more committed to a regular exercise regime throughout their later years; hitting it as hard as their inevitable physical infirmities would allow (TOP TIP: Tai Chi is an excellent example of a low impact physical exercise which improves strength and flexibility at any age. It requires no equipment and can be practiced wherever you happen to be). They tend to have been more engaged in a wider array of social activities. They tend to have been careful with their diet in the long term, favouring a healthy Meditteranean-style diet (see below for more) over a typical modern Western diet (often high in saturated fats and sugars). They also tend to have been more proactively involved with their local community and more motivated to seek regular mental stimulation. People are now being advised to adopt a variety of brain-healthy habits if they wish to reduce the likelihood of developing cognitive deficits that the progression of Alzheimer’s disease can, but does not always, induce.
Alzheimer’s disease is the most common of the many different types of dementia, affecting 10% of those over 65 and almost 50% of people over the age of 85 (Evans et al, 1989). Dementia describes a syndrome that involves progressive cognitive decline occurring at an accelerated pace compared to the very gradual loss of mental faculties associated with normal aging. Dementia can involve the deterioration of reasoning, judgement, thinking, mood control, language, understanding and, most famously of all, memory. Colloquially-speaking, Alzheimer’s disease is an almighty metabolic cock-up: a brain protein (beta-amyloid) is not constructed properly due to a misprint in the genetic recipe, causing it to form tiny sticky clumps (plaques) that develop between brain cells, preventing them from communicating with each other properly and eventually killing them off entirely. To make matters worse neurofibrillary tangles accumulate within brain cells, which also ultimately leads to cell death.
As Alzheimer's progresses brain cells are gradually killed causing brain regions to shrink and the gaps between them to consequently enlarge
Depending upon which brain structures these plaques form in, different mental functions can be disturbed. For instance, a brain structure that typically gets more than its fair share of amyloid plaques and neurofibrillary tangles in Alzheimer’s is the hippocampus. As I’ve described in a previous brainpost this brain structure is critical for the formation of memories and so when its function is compromised by the plaques and tangles of Alzheimer’s, people can become extremely forgetful.
To date, scientific research has yet to come up with a treatment to stop the formation of these amyloid plaques and neurofibrillary tangles, but there is evidence that drug treatments designed to boost the cholinergic neurotransmitter system can make symptoms less severe. Furthermore and extensive body of studies has gradually accumulated over the past 20 years to indicate that some people are able to tolerate the disruption caused by these plaques better than others (e.g. Katzman et al, 1988). The Katzman study described individuals who had shown no cognitive impairment whatsoever in life, yet post-mortem examination of their brains revealed that telltale signs of Alzheimer’s disease (the plaques and tangles) which had progressed to a considerable degree. This disparity begs the question: if two people’s brains are affected by the same degree of plaque damage, why does one continue to enjoy normal mental faculties, whilst the other suffers severe impairments to their memory, thinking and mood? The concept of “cognitive reserve” was introduced to describe brains which seemed to be able to compensate for the damage done by Alzheimer’s, presumably by using other brain networks not affected by the metabolic damage to take over certain cognitive tasks.
Alzheimer's disease involves plaques accumulating around the neural called "axons" that allow communication between different brain areas
A separate study, this time involving 593 individuals in New York over the age of 60 and on an “at risk of dementia” register, concluded that “increased educational and occupational attainment may reduce the risk” of developing Alzheimer’s disease. A more recent study conducted in the UK concluded that cognitive reserve is almost entirely mediated by childhood cognitive ability and educational attainment, whilst whether people had successful careers or not had very little influence. So does this mean that the only way to “plaque-proof” yourself is to study hard at school and stay in education for as long as possible? Well, yes and no. Yes – in the sense that this certainly seems to protect you from the ravages of amyloid plaque buildup. No – because there ARE things you can do to build up your cognitive reserve in later life, they just have nothing to do with what you do for a living and how good you are at it.
DIET
Diet may well influence the rate at which Alzheimer’s disease progresses, probably due to the negative influence of a modern Western diet on the brain’s blood vessels. In a recent article, prominent Alzheimer’s researcher Dr Scarmeas describes a study providing evidence that a traditional Meditteranean diet – characterised by lots of fish, unsaturated fats, vegetables, fruit and cereals – seems to protect against the development of Alzheimer’s disease. In a different study which used a mouse model of the disease it was suggested that coffee may help to slow the progress of Alzheimer’s disease by preventing build up of amyloid plaques.
LANGUAGES
A recent NYT article describes research into bilingual people who seem to develop the symptoms of Alzheimer’s on average 5 or 6 years later than those who speak only one language. This suggests that the cognitive demands of regularly switching between two or more languages may delay the onset of Alzheimer’s. Although this has yet to be proven, it is thought that speaking two languages may increase cognitive reserve by improving the function of prefrontal brain areas involved in executive control. Executive control involves mental functions like holding relevant information in working memory whilst ignoring irrelevant distractions, as well as other faculties relating to problem solving, planning and decision making.
FUTURE TREATMENTS
In the not-so-distant future it may be possible to replace brain cells damaged by the abberent metabolic processes of Alzheimer’s with fresh ones created from a person’s own skin cells. Other recent research has suggested that the amyloid plaques might cause memory problems by attaching to certain important neurotransmitters, and that drugs preventing this from happening may help to ease the symptoms of memory loss associated with Alzheimer’s disease. In light of the importance of early intervention to catch the disease before it causes too much damage new scanning techniques have already been developed to spot the disease before it induces any clinical deficits.
A variety of lifestyle changes can build up cognitive reserve, helping to keep dementia at bay and improving quality of life to boot!
In addition to these fortnightly brainposts you can also get DrJack’s daily #braintweet by following him on twitter.
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Dr Jack’s Memory Clinic on ITV1’s THIS MORNING – Mon 13th June 2011
2 Comments »Posted in Dr Jack on TV Radio StageJun 13, 2011
Read more »Dr Jack will be MAKING YOUR BRAIN BETTER FOR LONGER live on ITV1’s THIS MORNING
Dr Jack’s first appearance was on Mon 13th June covering the topic of how to improve your memory
Over the summer I’ll be making a series of contributions to ITV’s THIS MORNING. The aim is to get the nation interested in how their brains work and ultimately to help YOU get the most out of YOUR brain. I’ll offer easy-to-follow advice on how to get your brain firing on all cylinders each and every day.
I’ll be answering the questions that YOU want answered. Is your brain not what it used to be? Want to know what you can do about it? Bad with money? Ever wondered why you can’t kick your habits? Ever worry about your children’s development? You can either get in touch with your questions directly by clicking here, or get in touch with THIS MORNING via The Hub.
Topics I’ll be covering in detail will range from money management to memory, from love to hate, from happiness to sorrow, and all the way from child development to holding onto your marbles in old age. You most definitely CAN teach an old dog new tricks and it is never too late to start getting more out of your brain!
Each item will kick off with a discussion with Phillip Schofield and Co. on the sofa to explore ways in which they feel their own brains’ work well and not-so-well. We’ll then be asking members of the public to participate in experiments live in the studio. And we’ll meet some extraordinary people who’ll either demonstrate some amazing abilities or some shocking disabilities. Each item will be packed with useful tips, nudges and strategies for optimising your brain function. So, each week, you’ll be able to put my advice to the test to see how it can benefit your life by boosting your brain power.
Most people would agree that their memories are far from perfect. So, on Monday 13th June 2011, I’ll be showing you what part of your brain creates a MEMORY for people, places, facts and faces. I’ll be putting some members of the public through their paces to see how much information a noraml “working” memory can hold. You’ll even be able to join in the fun and play along at home. I’ll reveal a classic memory trick that is virtually guaranteed to boost anyone’s memory for lists of facts or any other kind of information you might need to remember.
So tune into ITV1 from 10:30-12:30 and SORT YOUR BRAIN OUT!
Academic credentials:
- Jack has studied Brain Biology for nearly 20 years
- Jack has a First Class batchelor’s degree in Neuroscience from The University Of Nottingham
- Jack earned his PhD in the Laboratory of Neurobiology at University College London
- Last year, Jack published a paper in the prestigious Journal of Neuroscience describing human brain scanning experiments that investigated multisensory perception; carried out during a post-doc at the Max Planck Institute for Biological Cybernetics
- Despite Jack’s extensive knowledge about the human brain, he is NOT medically qualified and so will not be able to answer questions relating to medical care.
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Hold On To Your Grey Matter – Take a Walk by Dr Jack
7 Comments »Posted in Aging BrainsOct 27, 2010
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Older brain on the left, younger brain on the right
From adolescence onwards we all begin to lose brain cells. As a consequence our brains gradually and inexorably shrink (compare the “old” brain on the left to the “young” brain on the right). In fact by the age of 80 your brain will occupy 15% less of the space within your skull than in the prime of life. Yet over the course of adulthood, as our brains are losing more and more cells, our knowledge and repertoire of skills nonetheless continues to grow as we accumulate more and more experience. How is this possible? Well, despite the incremental decrease in quantity of brain cells over the years connections between neuronal networks that are in regular and intensive communication with each other are selectively reinforced. This enables increased efficiency in execution of the mental processes that those networks support. Hence we can do more with less as we age. Sadly, for all of us, there will always come a time when the degree of brain cell loss is such that mental function begins to decline. In other words, if we all could live forever, dementia will inevitably strike at some point in time.
Although we cannot halt the process of grey matter loss completely, the good news is that we can slow down its progression. This month a study conducted at the University of Pittsburgh and published in the journal “Neurology” describes the influence of regular exercise on the rate of reduction of brain volume and cognitive function in 299 elderly individuals.It was observed that those individuals of this group of average age 78 who walked in excess of 6 miles per week had a significantly reduced rate of grey matter loss and consequently a lesser degree of cognitive decline. The greater the distance walked each week, the smaller the reduction in volume over a 9 year period within their frontal lobe, occipital lobe, entorhinal cortex and critically, in the hippocampus. My post last month described the vital role that the hippocampus plays in the creation and recall of long term memories.
This begs the question – how and why does exercise slow down the rate at which grey matter shrinks? An exciting possibility is that all that walking might actually increase the rate at which new brain cells are created; a process known as neurogenesis. This boost in the creation of new brain cells might help to compensate for the loss of old brain cells.
Evidence to support this hypothesis comes from research conducted over a decade ago suggesting, in the mouse brain at least, that exercise does indeed increase the rate of neurogenesis.Exactly why this happens is unclear, but I would propose that, given the hippocampus is heavily involved in navigation, particularly when it comes to flexibility in finding the best route from A to B, it would make sense for physical activity to trigger production of new cells in this brain area. A greater number of hippocampal neurons would presumably support a greater capacity to memorise routes and landmarks encountered whilst exploring the environment. This could feasibly convey a critical survival advantage by helping to prevent people from getting lost. Over the thousands of years of our species evolultion, getting lost was probably an excellent way of deleting oneself from the gene pool and so those with movement-triggered hippocampal neurogenesis may have been more likely to survive.
This seems a plausible (but by no means concrete) account of why older individuals who take regular exercise appear to have more grey matter and superior cognitive function than those who do not. Whatever the true explanation, it seems clear if you want to hang onto your marbles in the long term then it’s probably a good idea to take a regular stroll for the rest of your life.
You can follow Dr Jack’s daily #BrainTweets by clicking here, and pushing the “Follow” button.
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Brain Teasers = Brain Training by Dr Jack Lewis
18 Comments »Posted in Boost Your BrainFeb 17, 2010
Read more »Dr Jack Lewis is keen to get people motivated to get the best out of their brains, so has compiled a quick overview of brain training options:
Brain teasers are good for you. Brain teasers include word games, number puzzles, spot the difference, Where’s Wally-type games, attention directing or splitting challenges, general knowledges quizes and so on. Brain training simply involves perfoming various different brain teasers on a regular basis. Your brain constantly adapts to serve you better. The more often you perform a certain mental function the more the brain will do to make changes so that the next time you do it, you can perform it slightly faster, with a greater degree of success and more efficiently.
How do we know that practice increases the connections between different brain areas? Two brain imaging studies have demonstrated that when people practice a skill very hard for prolongued periods of time despite the fact that the changes happen at the ultramicroscopic level of the synapses where two brain cells meet the net effect of billions of these changes occuring over many months is that the grey matter gets larger in the part of the brain responsible for that function. The part of the brain that controls hand movements is significantly larger in professional string and keyboard musicians than non-musicians because of all the training they have done over the years to manipulate their instruments with split second precision. Another brain region, the hippocampus, creates and recalls memories particularly for geographical locations and is significantly larger in the brains of London Cabbies – who navigate around their city based on a sound KNOWLEDGE of every landmark, road and bridge – than in the brains of bus drivers – who simply drive the same route over and over again.
The synapses connecting various different groups of brain cells together that are responsible for perfoming a certain task, say a crossword for instance, are strengthened each time to try to solve the puzzle in order that they can function slightly more efficiently next time round. If you do the crossword every day, then the net effect of many slight overnight adjustments to the brain areas involved in searching your memory for suitable words that have a certain meaning, a certain number of letters and specific letters in at certain positions within the word, become noticably better after just a few days. The same goes for number puzzles. Or games that involve prolonged concentration. Or the ability to recall trivia when it becomes relevant to conversation.
We all know that practice makes perfect and the strengthening of connections between the relevant brain areas to enable more efficient communication between them is the reason why. Of course getting good at doing crosswords is not particularly useful in its own right, but the point is that once you become good at recalling suitable words for the sake of the crossword, you will also find it easier and quicker to bring the appropriate word to mind during conversation or when creating written documents – and that can be extremely useful.
There are numerous websites that have compiled a large variety of different puzzles (http://www.brainbashers.com/puzzles.asp) and various others where you can try out electronic versions of classic physical puzzles like the Tower of Hanoi (http://www.mazeworks.com/hanoi/index.htm). However these all pale into comparison next to custom-designed brain training games such as those available at Lumosity (www.lumosity.com), which have not only the advantage of a much more aesthetically-pleasing look and feel of games that are genuinely fun and engaging to play, but also as you have to log in to play (they offer a free 30 day trial) you can keep track of how your performances improve over time.
Nintendo DS were the first console manufacturer to produce and market games with the aim of improving brain function which all started with the release of Dr Kawashima’s Brain Training in 2005. This predominantly involes some quite predictable tasks like the Sudoku number puzzles, simple rapid-fire arithmetic, but also some unexpected treats like the Stroop Test (naming the colour of the font ignoring the meaning of the word which can be tricky when the word RED is written in blue font!) which take advantage of some pretty nifty voice processing software. I must admit I found myself thinking “can I really speak to this machine?”
The effect of the advertising campaign that accompanied the release of this game was quite profound as it not only encouraged everyday consumers to purchase Nintendo’s products, but more importantly sent out the message that the brain is something that you can do something pro-active to improve; a concept that has been long-accepted to be the case in children but the mantra “you can’t teach an old dog new tricks” meant that this was rarely considered to be applicable in adults. Such a message is particularly enticing for people entering into old age, for whom the prospect of holding onto their marbles for as long as possible is extremely desirable and thus motivating. In this regard the key thing to remember is that, as far as the brain is concerned, it’s a simple matter of use it or lose it. Exercising brain areas involved in problem-solving by tackling word games, logical reasoning problems, memory challenges and number puzzles keeps such mental faculties in tip-top condition. If you don’t continue to use these mental abilities then they will fall into disrepair because the brain receives no indication that connections between appropriate areas should be maintained and reinforced. The upshot: it is never too late to improve your mental fitness. By emulating the lifestyles of individuals enjoying a healthy brain in their 80s and 90s, who have regular social interaction, cards games, read extensively, stay physically active and challenge themselves daily with various puzzles and quizes, the odds of being afflicted by Alzheimer’s disease are reduced by 25%.
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This website contains everything you need to know about Dr Jack Lewis – brain scientist, television presenter, motivational speaker, writer and neuroscience consultant.