• Fighting Dementia with Sea Hero Quest

    shq-logoAs we move around in the world we develop a sense of how to get from A to B. This relies heavily on the hippocampus, a brain structure nestled deep within each of the temporal lobes, responsible for many functions vital to cognition such as memory and navigation. This is the brain structure famed for becoming physically larger as a result of all the practice driving around London that the drivers of London’s famous Black Cabs have to accrue before they can pass “The Knowledge.” Whilst their memory for the 25,000 roads and 20,000 major landmarks that enable them to instantly reel off the route they’d take to get from one place to another is extraordinary, for the 33% of those born in 2015 will live long enough to develop dementia at some point in their lives this situation is reversed. Difficulties with navigation, even familiar routes between places visited many times before, is one of the problems in daily life that can herald the approach of full-blown dementia. Understanding the normal trajectory of changes in navigational ability over the lifetime of a health brain is a vital first step. With or without dementia our abilities to memories complex routes becomes slowly but surely compromised by the normal processes of age-related cognitive decline. We need to know what is normal for each age group before we could be in a position to use a steeper than normal decline in navigational ability as an early warning signal, ideally before any memory deficits have had a chance to rear their ugly heads. As our understanding of the metabolic processes that lead to various forms of dementia improve, this early warning could prove to be a vital mechanism in triggering prophylactic treatments early enough to slow down disease progression.

    memoriseHugo Spiers, a memory researcher and neuroscientist at University College London, launched a smartphone game in 2016 called Sea Hero Quest, which aims to do just this. Over 2.5 million people have played this surprisingly fun, engaging and challenging game so far, generating the equivalent of an astonishing 9,400 years worth of lab data. The game involves memorising a map of waterways around which a series of numbered buoys have been distributed. Once you’ve planned the journey you’re going to make and tucked it away in your working memory, the map is then taken  away and your job is then to steer your little fishing boat (increasingly customisable as you progress through the game) by tapping the left or right side of the touch screen. The terrain varies from idyllic sandy paradises to rainy, foggy, bumpy rides across perpetually undulating swell. Thanks to the funding from Deutsche Telekom and Glitchers – the tech-gurus who actually created the game – the graphics are beautifully rendered, the gameplay is smooth and unlike most games designed to answer important scientific questions, every aspect of the user experience is highly polished. As was the delivery of the first results announced at SfN 2016 and summarised below by the man himself…

     

     

    buoyPersonally I was surprised by how hard some of the levels were. I play a lot of brain training games (e.g. PEAK Review, BRAIN AGE 2 Review ), just to keep myself up to date on the latest offerings, and am now accustomed to finding myself able to get maximal scores on most categories of games pretty quickly through daily play. Not Sea Hero Quest. Once I got past the easier earlier levels, I often found myself getting lost in the mist, or going round and round in circles having forgotten how to get from buoy 3 to buoy 4. As a consequence, not only did I help scientists like Hugo Spiers and colleagues from the University of East Anglia and Alzheimers Research UK to generate data (anonymously, you only have to give your age) but I also got an insight into what the future might have in store for me should I become one of the unfortunate 1 in 3 that get clobbered by dementia in my post-retirement years. As you progress from level to level you periodically get to chase down one of a large variety of sea monsters. Having dodged innumerable obstacles along the way the monster in question eventually leaps out of the water at you and your task, is to resist the temptation to hit the button on your camera to take a photo of the rare and exotic sea beast in question, until the very last second when the captured image is at its most aesthetically pleasing.

    Overall, I found playing this game great fun, very challenging at times and doubly satisfying knowing that it would, in some small but meaningful way, help science to get some much needed answers about how the human brain keeps track of where it is and where it’s going in health, so we can better understand when this system breaks down in disease.

    img_1517I would just like to take a moment to applaud @HugoSpiers and collaborators for finding a way to genuinely enable people to #gameforgood. Hats off to you all… your Cannes Lion was thoroughly well deserved!

    In addition to these monthly blogs you can get daily brain tweets about other amazing developments in the world of neuroscience by following me on Twitter (@DrJackLewis). And for a fortnightly appraisal of the latest quirkly stories from the wonderful world of science on general there’s always the totally free Geek Chic Weird Science podcast available from iTunes, Podbay, Libsyn and many others.

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  • Announcing the Birth of our Beautiful New Book

    On the 6th October 2016 the book of the podcast that is Geek Chic Weird Science hit the shelves of bookshops all over the UK. A couple of days prior to this my co-author (and co-presenter of the podcast) Lliana Bird and I threw a little party to celebrate this milestone with a few family and friends.

    micewhosing_twitpic3dd4078I’m quite literally just running out the door to record our 60th podcast tonight! For those who’ve never had a chance to listen, every couple of weeks we talk about the latest weird and wonderful science stories to hit the press in the past few days. We tend to favour the conversation starters: the whacky techy tales that people might pull out of the bag around the dinner table, at work/school or in the pub to spark a conversation around the latest strange/surprising scientific discoveries.

    By the time we got about episode 50 we had an archive of about 200 or so of these science stories. So we thought: why not write a book. Happily the publisher Little Brown were prepared to publish it under their Orbit imprint and with only four months to bash it out we just about managed to hit the deadline. It’s a bit ragged in places, a few errors and slight inaccuracies here and there, but given the incredibly limited time we had to get it done I think we did a pretty good job.

    We’ve had some tremendous reviews from the likes of Brian Cox and the Times Science editor. Some of our stories have already been picked up in the NME and the London Metro. And with Noel Fielding’s beautiful original artwork adorning the front cover we have high hopes for some good sales over Christmas.

    mumanddadWe dedicated the book, with love to our parents, but also to Richard Boffin who has been our “sound guy,” editing our podcast, adding the music and sound effects and getting it up on iTunes, libsyn, podbay (click any of these links if you want to have a listen) and various other podcast media month after month for over two years now. Thanks Boff – you’re a legend!

    A huge thanks must also go to our thousands of podcast listeners around the world – we’re really grateful for your continued support – and we really hope you enjoy the book, not to mention the quirky and amusing illustrations our talented artists conjured up for us.

    Mice Who Sing For Sex by Lliana Bird and Dr Jack is now available to buy online and in all good bookshops like, my personal favourite, Waterstones.

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  • Porn Brain

    Last summer I was invited by the lovely people at the Latitude Festival to participate in a debate at the Literature Tent on the impact of online pornography on society.

    pornperspectiveonstage

    It was chaired by Dr Suzi Gage (@soozaphone) of Bristol (and by now Liverpool) University, known for her popular Guardian science column and podcast Say Why to Drugs. The other panelists were Martin Daubney (@MartinDaubney), former editor of lad’s mag Loaded for eight years and theatre-maker Christopher Green (@Kit_Green) creator and player of comedy Country ‘n’ Western heroine Tina C.

    My role was to bring the neuroscience perspective, Martin the media perspective and Chris was taking the arts angle. I got prepared quite a few weeks in advance and was stunned by what I found lurking in the academic literature. So I thought I’d share my main findings with you here in this month’s blog.

    When people think of addictions, compulsive consumption of various psychoactive substance is usually the first thing to spring to mind. Much research has demonstrated a hyper-responsiveness of the reward pathway – the ventral tegmental area in the midbrain and nucleus accumbens in the ventral striatum in particular – to drug-related images in the brains of people addicted to recreational drugs like, for example, cocaine. This body of research also demonstrates that the activity generated in the reward pathways of drug addicts to pleasant images of scenes unrelated to drugs, is somewhat diminished compared to non-drug takers. In other words, excessive consumption of drugs seems to subtly rewire the reward pathway so that it becomes more sensitive to visual scenes relating to their preferred recreational drug and less so (than normal) to everything else. It seems this is not just limited to drugs, a similar impact on brain function is seen in people who over-consume porn too.

    img_0510It is important to bear in mind that the reward pathway is not only important for generating feelings of happiness when we participate in pleasurable activities, but it’s also instrumental in predicting what choices might bring us rewards in the future, which means it is critically involved in decision making. It’s role in helping us evaluate the benefits of one option over another extends to the point where this system, in combination with other nearby brain areas, can be thought of as providing the very drive that motivates us to pursue one course of action over another.

    In recent times, research into excessive consumption of various products accessed through the internet – online gaming, gambling and pornography, to name but a few – also leads to behaviours that have all the hallmarks of addiction, not to mention the altered neurological responses outlined above. There has been some resistance to this idea in various academic communities, but the movement to have these “arousal” addictions included in handbooks of psychiatric illness symptom classification, and in particular the DSM-5, is starting to gather momentum.

    On the basis of a huge survey investigating the pornographic consumption and sexual experiences of 28,000 Italian teenagers it seems that, for about one in ten boys who consume explicit online pornography on a daily basis, the habit is interfering with their ability to engage in real life sexual activities:

    It starts with lower reactions to porn sites. Then there is a general drop in libido, and in the end it becomes impossible to get an erection

    Carlos Forsta, President of the Italian Society for Andrology and Sexual Medicine.

    This may at first glance seem to fly directly in the face of the stereotype of the ultra-horny teenage boy, brimming full of the very sex hormones that would usually ensure a hair-trigger sexual response to any possibility of coitus. But in light of research conducted many years ago by joint winner of the 1973 Nobel Prize for Physiology or Medicine, Nikolaas Tinbergen, it starts to make a lot more sense. In experiments conducted with “supernormal” stimuli, he observed that birds preferred to sit on larger than normal and / or more colourful eggs constructed from plaster, rather than their own real eggs. Similarly, herring gull chicks would peck harder and more often at a fake adult herring gull beak with brighter or more numerous red spots than the real thing, in a vain effort to elicit a regurgitated dinner. The point is that the larger than real life stimuli seem to have short-circuited the birds’ primal instincts leading to a preference that would ultimately be deleterious to the survival of the bird’s progeny.

    It seems that the ubiquitous availability of explicit internet pornography is leading to a similar scenario in modern day internet addicted teenage boys. A subconscious preference for artificial, supernormal, explicit porn over actual sexual partners seems to be occurring with alarming regularity in adolescents who let their penchant for titillating pornographic films get out of control. In his TED talk entitled “Why I stopped watching porn” Ran Gavrieli gives an excellent and compelling account of some of the key differences between what pornographic films actually show and the relatively tame sensory stimuli involved in genuinely satisfying, intimate sexual behaviour between consenting adults.

    Essentially, he points out that themes typically conveyed on free online porn sites, such as female subordination and extreme close ups of penetration to name but a few, are the human sexual equivalent of the brightly coloured, super-sized eggs and beak markings from Prof Tinbergen’s experiments (just not in so many words!). Porn is a supernormal stimulus, dominated by explicit close ups of penetration that you simply can’t reproduce in reality (the penis and eyeballs will always be separated by a set distance, unless you are exceedingly flexible, of course). Inevitably the real thing pales into insignificance by comparison after sufficient daily use of explicit porn of virtually infinite variety. No wonder boys are struggling to get it up!

    img_0538This isn’t to say that there is no place for pornography in society. Regardless of your attitudes on this topic, it certainly isn’t going away any time soon. However it may be useful for porn fans to bear in mind the concept of everything in moderation. Once one genre of porn is no longer arousing there are many other categories to choose from. Once the relatively soft porn is no longer stimulating, casual browsing will always yield more explicit options. Eventually the kind of sexual activities we are likely to have access to in real life become insufficient to yield an erection for long enough to reach climax, which will inevitably lead to relationship problems. And nobody wants that.

    The good news is that abstinence from pornography is usually sufficient to enable normal biological sexual function to eventually return. Interestingly, in older men this takes two months, whilst in younger men it can take much longer: four to five months. Find out more in the Latitude Podcast of the Porn Perspective Debate.

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  • 2016 Showreel

    In my 8 years of presenting / contributing as an expert to TV shows I’ve appeared on every British terrestrial television channel and half a dozen or so international cable and satellite channels. My most recent series Secrets of the Brain is available to be streamed for free from anywhere in the world on the dedicated ultra high definition digital channel insight.tv (also on sky channel 279 in the UK). It’s without a shadow of a doubt the best presenting work I’ve done so far and it even got shortlisted for an AIB award.

    Here’s my brand new showreel dedicated entirely to SotB.

    Hope you like it…

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  • Brain Training Review of PEAK by Dr Jack

    As my regulars will know I like to keep abreast of movements in the brain training game market. I’ve reviewed Nintendo DS’s titles from the Dr Kawashima, Lumosity and even some that weren’t specifically designed to improve cognitive functions, yet arguably do. Christmas before last I subscribed my parents up to Lumosity on the iPad. 24 months later my dad still plays on a regular basis. He’s up to 99.9% for his age group in every category bar 1 (where he is up to 99.7%!). This year I’ll be subscribing them to PEAK instead, because having regularly used it on my phone to kill time whilst in transit (or on the throne) for the best part of a year I genuinely think the (relatively) new kid on the block wipes the floor with Lumosity.

    All the major players tend to include a core set of “classic” brain training games that are clearly inspired by neurological tests that have been around for many decades e.g. Go/NoGo, Stroop, N-back etc. Unlike their rivals who seem to be happy with the basic versions, PEAK seems to continually evolve each game by adding a twist or making each game a little bit tougher.

    IMG_7104Take for instance working memory training – the only games for which there is any half decent published data in the peer-reviewed science literature supporting claims that it can actually improve cognition (and even that evidence is hotly contested!). The spatial working memory training games like PERILOUS PATH (memorise the position of the mines whilst they’re briefly displayed and then trace a path around them from random start to finish points), MEMORY SWEEP (remember and reproduce the position of illuminated blocks in larger and larger grids) and BOUNCE (guess the finishing point of a laser beam sent bouncing across angled mirrors distributed across the grid after a brief glimpse of where they are) have all been done before, but these are all great versions.

     

    PEAK also takes simple versions of classic brain games and takes steps to improve them. For example, RUSH BACK involves simply answering whether each presented image is the same or different as the previous one. A 1-back task like this hardly challenges working memory because you can use iconic memory (the visual impression left in the mind’s eye for a few tens of milliseconds after any object disappears from view). They quite rightly class this as a test of “focus”, because if you lose concentration then it is easy to accidentally push the wrong button. Particularly when you’re trying to go as fast as possible to maximise points. Yet over the months they’ve introduced RUSH BACK PLUS – which is a 2-back task and two other aesthetically appealing variations on this game:

    TUNNEL TRANCE – progresses from the 1-back task to the 2-back (same as the image before last?) to the 3-back (same as the one before the one before last) – this really has the potential to genuinely help people hold more information in mind when they are performing a real life task. It probably goes up to 4-back and beyond… if so, I simply haven’t performed well enough at the 3-back task to get promoted to the next level.

    PARTIAL MATCH – the task is to rapidly decide whether the image is identical to the last image, completely different, or partially the same (i.e. same colour but different shape or same shape but different colour). This I have never seen anywhere before. I appreciate that PEAK are putting in the effort to innovate and that it took me a surprisingly long time to get the hang of. I’m always mindful that the harder something is to get the hang of, i.e. the more a brain finds it to be a challenge, the more resources are likely to be invested in reinforcing the relevant neural pathways in an effort to adapt the brain to improve that particular mental function. Speaking of which another game that was introduced very recently definitely deserves a special mention… HAPPY RIVER

    A common symptom of depression is the tendency to ruminate over negative thoughts or emotions. An effective but simply remedy is to develop the habit of dwelling instead on the positive whilst disregarding the negative. Bear this in mind as you read on because I’m convinced that HAPPY RIVER can only be a power for good, which suggests that PEAK really are keeping an eye on the latest developments in psychology and neuroscience to find inspiration for their new game pipeline.

    HAPPY RIVER involves reuniting a baby elephant with its mother. They are on opposite side of the banks of a river that have several rows of words streaming across it either from left to right or right to left. Each of the individual words acts as a raft. By tapping the screen the baby elephant hops forward. Your timing has to be accurate or else you’ll fall into the gaps between each word raft. You also have to be strategic because only those words with positive emotional overtones provide safe passage. Step onto a negative word and you’ll be tipped over into the rapids. So to successfully reunite the baby elephant with its mother you have to focus on the positive and avoid the negative – hence PEAK have created a game that could well encourage a habit that could ever so slightly nudge players towards a more positive outlook and greater mental health.

    IMG_7105FLIGHT PATH challenges many different cognitive capacities. You start with a bird’s eye view of some lush green fields at the middle of which are 4 landing spots for airships that fly into view from top, bottom, left or right of screen. Each airship has a different letter and moves at a different velocity. Your task is to plot the movement of each airship so that they line up on the ground in an order that spells a 4-letter word. The airspace can get pretty crowded so half the challenge is to do what all air traffic control professionals do so well – stop the aircraft from smashing into each other and showering the sky with debris. For this game you need to think strategically, flexibly, linguistically, constantly updating the flight paths for a steadily increasing number of craft whilst simultaneously keeping your eye on an icon in the top right corner to win extra points. Although there is no published data yet to prove it, my hunch is that having to divide your attention across so many competing concerns and continually re-evaluate your priorities, will tune up brain pathways that would surely come in useful for any high pressured professional.

    In addition to these monthly brain blogs, you can subscribe to my weekly science podcast (or get it on libsyn) and follow me on Twitter (@drjacklewis) for a daily dose of news articles describing the latest breakthroughs in brain science.

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  • Bionic Brain Adaptations by Dr Jack Lewis

    luke-skywalker-arm-chopFirst I met a bona fide bionic man in Cambridge – that got me thinking about an essay I wrote whilst in my undergraduate neuroscience days. It explained, in great molecular detail, the obstacles that would have to be overcome for a robotic limb to ever adequately replace the functional repertoire of a severed one. In other words I described what it would take to do a “Luke Skywalker” (for those who actively avoid Star Wars: Luke is the hero who get his arm chopped off in a light sabre battle only to have an operation that replaces the severed limb with a fully-functional robotic one that he controls as effortlessly as the original).

    luke skywalker armSecond I flew to Kyoto – to interview the Godfather of Androids, a man who has created some of the most sophisticated human-like robots in the world. Over ten days of filming I must have come face-to-face with over a dozen robots. Each time I thought back to something that happened, totally spontaneously, during a game of Jenga with Nigel Ackland – my real life Luke Skywalker.

    Finally, Nigel performed a manouevre with his robotic arm that no human could with a mortal one. This event brought to mind a classic series of Japanese neurophysiology experiments from the lab of Professor Iriki. These studies expanded our understanding of how brains keep track of the space around us. In particular, how brains distinguish between parts of the environment that can be influenced with a extended arm (plus any tool that provides an extension), and parts that cannot (NB see in particular the original observations from 1996).

    Consequently, this month’s brain blog is dedicated to a combination of…

    Robotic Technology, Human Determination & Neuroplasticity

    neglectThe parietal cortex of the primate brain (including the human primate) is responsible for, among several other important functions, our awareness of space. For example, damage to the patch of brain tissue that resides where the parietal lobe borders its temporal and occipital lobe neighbours can lead to neglect if it occurs on the right side of the head (See the images in this free classic paper on neglect if you want to see exactly where in the brain this is) – resulting in the person’s awareness of the left side of everything being highly compromised. Give someone with neglect a piece of paper with circles drawn all over it, asking them to place a mark at the centre of each, they only mark circles on the right side of the page. Ask them to draw a clock face and they will not draw the numbers on the left side (i.e. having successfully drawn a circle and the hours from 12 to 6 on the right hand side, they’ll typically omit the hours of 7 – 8 – 9 – 10 and 11 because they lack awareness of what should be on the left side of a clock face). They will only eat food from the right side of their plate. They will often even only shave the right side of their face, dress the right side of their body. Their awareness of “leftness” has been fundamentally compromised. Such is the importance of the parietal cortex to our awareness of space.

    iriki macaqueTowards the end of the 90’s and early 00’s researchers working with Japanese macaques trained to reach for food rewards observed that certain neurons would become activated if the treat was placed within arm’s reach. If the primates were provided with a croupier’s rake (usually used in casinos to collect up chips on gambling tables) then neurons representing nearby space that was previously out of reach would become activated once they gained experience using this simple tool to drag the food rewards towards them. The researchers even took it a step further by providing two rakes, one with a short handle and one with a long handle. Neurons representing space out of reach with the short handled rake became recruited into the “network of reachable space” when the macaques figured out they could use the short rake to pull the long rake closer and then use this to drag the treat from the opposite side of the table. Keep this in mind as you read the following account of bionic brain adaptation.

    Bionic Brain Adaptation?

    Version 2Nigel Ackland is a real life bionic man since a nasty industrial accident left his arm mangled and several subsequent botched surgeries led to his decision to have his right arm amputated from the elbow down. Shortly after this operation, he started to develop pain in his phantom limb. His NHS-issued “pincer” enabled him to gain some additional dexterity, but it did little to diminish the phantom sensation of his fingers and wrist locked into an extremely uncomfortable position. However once he started using a cutting-edge bionic arm, equipped with various pre-programmed five fingered hand movements operated via neuronal signals passing from his brain to the muscles at the end of his arm stump, not only did the phantom limb pain start getting better, but the phantom limb started extending gradually from his stump into the hand and fingers of his bionic arm.

    bebionicWhilst playing Jenga with him for my new series Nigel did something quite remarkable, triggering the memory of those Japanese macaques. Reaching with his bionic arm to grab an awkwardly positioned brick, from his side of the table he could only present the back of his hand to the block he was after. Unlike the rest of us mere mortals Nigel can rotate the hand of his bionic arm at the wrist by 360 degrees. To reach the brick in question he simply rotated his hand 180 degrees to face the other way, and then grabbed the block he was after with his bionic thumb, fore- and middle fingers in the usual way. It immediately occurred to me that people with bionic limbs – who can do things a normal human limb can not – may be awakening neurons in their parietal cortex that represent areas of space that have never before been recruited into the “network of reachable space” in the history of our species. Now that is very cool.

    In addition to these monthly brain blogs, you can subscribe to my weekly science podcast (via itunes, via libsyn) and follow me on Twitter (@drjacklewis) for a daily dose of news articles describing the latest breakthroughs in brain science.

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  • Brain Benefits of Mindfulness – PART 1

    Hippie-MeditationI used to think that the practice of “mindful meditation” was exclusively the preserve of yogis, Buddhists and New Age hippies fresh back from an extended voyage of self-discovery around Asia. If you’ve ever found yourself caught up in a conversation with an over-enthusiastic traveler fresh back from their adventures you’ll know what I mean. Such folk have usually undergone a wholesale transformation from fairly conventional individuals into barefoot, sandalwood-scented, Thai-dyed, hemp shirt and trousers wearing, bead bracelet bedecked eccentrics who preach the stupidity of capitalism and the supremacy of the compassionate mind-set at any and all available opportunities. My attitude has changed fundamentally in recent months.

    A recent review paper (in Nature Reviews Neuroscience, no less) evaluating the flurry of scientific investigations into the possible benefits of practicing mindfulness that have accumulated over the past ten years or so, has given me a fresh perspective. To my surprise it turns out that there is plenty of early evidence attesting to “beneficial effects on physical and mental health; and cognitive performance.”

    WHAT IS MINDFULNESS?

    Cluttered MindMindfulness is actually a very simple concept to grasp, if only we’d give it a half chance. From the moment we wake to the moment we go back to sleep our minds are cluttered with innumerable thoughts.

    These thoughts tend to focus on the past and the future: conversations, experiences and interactions that occurred in the past and hopes, ambitions, fears and other concerns regarding the future. Mindfulness encourages the development of attention directing and emotional regulating capacities that enable us to focus on the present moment. Ultimately, by getting in the habit of focusing on what we target with our conscious awareness, rather than just allowing ourselves to be buffeted by whatever stimuli, thoughts or feelings happen to flicker through our minds, we can achieve a greater self-awareness.

    GETTING STARTED

    Mindful-Happiness_Breath-Meditation-Practices-BreathingPaintingThere are many different ways of achieving a mindful brain state but typically the beginner is encouraged to start by focusing on their breath. They are asked to breath deeply, in and out, right into the belly to ensure their diaphragm is being used to full effect. Whilst performing these simple actions they are regularly reminded to bring their attention back to their breath whenever the mind wanders elsewhere, to notice the cool air passing in through the nostrils on the inhale and the warm air passing out again on the exhale. After a few minutes of this, you are usually instructed to re-direct the focus of your attention on different body parts, moving systematically around the body. Notice the feeling of clothing on skin, upward pressure of the floor (or the chair) on your buttocks – move your mind’s eye from your toes, gradually up through the legs, into hips, up your back, across your shoulders and down your arms to your finger tips.

    FOCUS AND RE-FOCUS YOUR MIND

    When thoughts pop into your head, as they invariably will, the idea is not to block them or force them out, but simply to acknowledge them without engaging too deeply; focusing attention back on your breath, or touch sensations in a certain body part.

    FocusIt sounds extremely simple (too straightforward to result in any meaningful benefits surely?!) but most of us are ingrained with deeply entrenched habits of thought such as worrying about events in the past or future or perpetually seeking some form of stimulation that it can take a while to achieve the goal of quiet contemplation of bodily sensations for more than 20 or 30 seconds at a time. But for those who stick at it – regularly, intensively and consistently over many weeks and months – and gradually build their ability to stay in this mindful state for 5, 15, 30, 60 mins at a time, a wide variety of benefits are achievable. And the latest neuroscience studies into mindfulness are homing in on what it going on inside the brain as a result of all this practice.

    To find out about how mindfulness changes the brain please click here.

    If you love science geekery then my weekly science podcast Geek Chic’s Weird Science may well be right up your alley. It’s available on iTunes, audioboom, libsyn and podbay, with the delectable Lliana Bird who presents every Fri and Sat nights on Radio X.

    I also regularly share the best of the day’s neuroscience breakthroughs on Twitter so if you’d like to follow me, please click here –> @drjacklewis

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  • Brain Benefits of Mindfulness – PART 2

    In part 1 of this blog I broadly described the benefits of mindfulness and what it involves. Here I dig into the detail, outlining the parts of the brain that appear, on the basis of a recent review of many brain scanning studies, to be most consistently impacted by the regular practice of mindfulness.

     

    NEUROPLASTICITY IN ACTION?

    Attention

    Using MRI scanning to focus on differences in the physical structure of brains has revealed that the anterior cingulate cortex (highlighted in yellow in the below image), often implicated in studies of attention, is physically thicker and the underlying white matter denser in practitioners of mindfulness who are highly experienced as opposed to those who are relatively inexperienced.

    MRI_anterior_cingulate

    Emotional Regulation

    Moderate to severe stress is associated with high levels of circulating cortisol (a “stress” hormone). This is associated with increased density in the amygdala (highlighted in red in the below image) – a structure deep within the tips of the left and right temporal lobes and vital for orchestrating rapid responses to perceived danger. Decreased tissue density is observed within several prefrontal regions and the hippocampus – which also resides within the core of the temporal lobes – serving several memory-related functions and vital for many aspects of cognition. Regular practice of mindfulness appears to reverse this. Cognitive impairment is reduced and presumably an increase in synaptic connectivity accounts for the increase in tissue density within the hippocampal / prefrontal cortex. The enlarged amygdala shrink – presumably due to reductions in the number of synaptic connections between neurons in this region – which is also associated with a reduction in anxious feelings /  the attenuation of heightened perception of threat, back down to normal levels.

    amygdala_mindfulness

    Self-Awareness

    The default mode network (DMN) describes a group of brain areas that are activated in MRI brain scanning studies when participants are “in between tasks”. At first these activations were thought to reflect the brain at “rest” or in “default mode.” After a few more years of research, during which this same set of activations cropped up under circumstances that couldn’t reasonably be described as “restful” the original conclusion was revised. Considering all the studies in which the DMN kicked into action it seemed much more likely that it relates instead to “mind-wandering.”

    GhostbustersMarshmallowmanIn the original studies, when the participant was instructed to “rest” they would invariably use this period to self-reflect or daydream about something completely unrelated to the experimental task (I certainly did when I volunteered for various MRI studies – it’s impossible not to – anyone that’s seen Ghostbusters should know that).

    A couple of years ago when I conducted a series of interviews (British Neuroscience Conversations) with various big hitting neuroscientists at the British Neuroscience Association’s conference, neuropsychopharmacologist Prof David Nutt pointed out that, if our “ego” or the “self” lives anywhere in the brain the Default Mode Network is the best candidate.

    DMN in meditationThe medial prefrontal cortex (labelled DMPFC for the dorsal/upper part and VMPFC for the ventral/lower part) and posterior cingulate cortex (PCC), i.e. the core DMN regions, were less active in experienced versus inexperienced mindfulness practitioners. As one of the primary aims of many mediation practices is to selflessly accept thoughts and feelings in a non-judgemental, compassionate way – the reduction in these neural correlates of “ego” may well reflect a degree of success in this endeavour.

    So inspired have I been by these revelations of fairly solid early evidence attesting to a likely neuroplastic impact of regular practice of mindful meditation on brain areas involved in modulating attention, emotional responses and perhaps even ego that earlier in the year I went to Mykonos for a retreat to immerse myself properly (opening the invitation to anyone who faniced coming along).

    Since then I’ve gone on to develop a #brainboost campaign for Weight Watchers in order to help tackle the obesity epidemic by getting people’s brains ready for healthier eating by practising mindful eating, performing a bit of daily brain training to boost their working memory and learning some simple brain hacks, all with a view to eating more strategically.

    slider-eating-mindfully-bookDuring my research for this project I came across a nice little book on mindful eating that I would highly recommend: it’s called Eating Mindfully by Susan Albers. Personally I find a lot of books on this topic extremely cringeworthy, but Susan Albers describes the practical tips on how to avoid mindless / emotional eating through mindfulness in a very straightforward manner.

    My own book “Sort Your Brain Out” includes a chapter on the kind of foods and eating habits that are good and bad for the brain. In addition, I do a weekly science podcast available on iTunes, audioboom, libsyn and podbay, with the delectable Lliana Bird who presents every Fri and Sat nights on Radio X. And I regularly share the best of the day’s neuroscience breakthroughs on twitter (@drjacklewis).

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  • Adverts Encouraging Use of Tech to Subdue Kids Could End In Tears

    A new Vodaphone advert hit our screens recently and I hate it with a passion. My gym seems to have it on a loop at the moment and every time I see it I progress through a variety of emotions ranging from mild disappointment to abject rage. It starts innocently enough, depicting a bus weaving it’s way across a patchwork quilt of luscious fields. England’s green and pleasant lands, we might assume. The driver is keeping a kindly eye on his customers through the rear view mirror, a young woman is dozing on her man’s shoulder, a suited middle-aged businessman is reading his newspaper and a teenage girl is listening to music on her headphones. One row in front of our lovers a mum finds herself unable to pacify her crying toddler. We’ve all been there. It’s not a pleasant experience when the calm and tranquility is pierced by the ululations of an irate infant child. One-by-one the cast make faces betraying their discontent over the bawling nipper. In such situations – what can you do? Other than grin and bear it?

    VodaphoneAdOn this particular bus, in this particular locale, a hero is at hand. In a bid to bravely defend his belle from her rude awakening, that self same man (one row behind the squalling squib) unsheathes his smartphone. And using the “Power of 4G” summons a cartoon to his screen with which to mesmerise and thus pacify the aforementioned disconsolate child. Miraculously the tears dry up immediately, the sobbing quickly replaced by smiles and giggles of joy. Peace reigns over the bus once more and glances of appreciation ensue.

    The boyfriend/man/husband presumably earns himself a family-sized haul of brownie points from girlfriend having demonstrating not just a strong capacity for empathy but a clear aptitude for child wrangling (what a great dad he could be!). Mum is palpably relieved that the blight to everyone’s day has been appropriately dealt with by this marvellous stroke of genius (so embarrassing when he plays up like that!). Even the stressed out businessman seems to have gone a few shades of purple lighter. The teenage girl goes as far as taking off her headphones, momentarily, to revel in the delicious, unexpected peace and quiet before breaking into a private smile. In the estimation of these fine bus passengers, the holder of the phone is clearly nothing less than an absolute legend.

    Dora_The_ExplorerDora the Explorer is the chosen cartoon and it’s a good choice (a much better choice than Teletubbies, for example). Inexplicably, the language she utters in this British version of the ad is Spanish. I may be showing my ignorance here. Perhaps Dora the Explorer is always aired in it’s original tongue. But it occurred to me that just maybe the ad was cheekily alluding to possibility that the kid might even start to pick up a new language as a fortuitous side effect of this timely intervention. Such is the “Power of 4G”. It’s just a shame that the evidence from several studies indicates that too much screen time spent goggling at idle entertainment displaces valuable time doing other things in the real world that really facilitate a child’s neurodevelopment. Surely encouraging the habit of endlessly distracting kids with smartphones, tablets and laptops throughout their entire childhood is only going to perpetuate this problem, not to mention fueling a boom in short-sightedness.

    It’s not just Vodaphone who are at it. Nissan have also released a TV ad recently for the Pulsar. Excitingly it has automatic braking. For those unfortunate circumstances where the driver’s brain is distracted away from the road at precisely the moment the vehicle in front decides to slam on the brakes without warning. The vital milliseconds saved by circumventing the pesky human can make the critical difference between a dangerous fender bender and safely completed journey.

    Nissan Ad Zombie ChildrenThe key message throughout is that the car is carefully built around the driver and therefore every conceivable problem has been anticipated and addressed. In the closing scene two children appear in the back seat fidgeting, shouting and generally being… well… children. In the blink of an eye technology has magically teleported into their midst – the rowdy boys instantly transformed into well-behaved, docile and, most importantly, silent little angels: one absorbed by a tablet, the other gazing out of the window listening to something on a pair of expensive looking headphones (let’s hope it’s my podcast). That’s right kids. Do not interact with each other. That would just cause a disturbance to your father, or whoever he is. Communication must be discouraged when in ear shot of your elders and betters. And remember: silence is golden!

    My issue with these ads is not Susan Greenfield-esque. I don’t believe that technology is good or bad. But I do think that to unquestioningly consume limitless hours of screen entertainment at the expense of all other activities would have negative consequences for brain development across childhood. My objection to these ads revolves around that fact that they are normalising, if not positively encouraging, child-rearing behaviours that are likely to be deleterious to the best interests of the next generation.

    Study after study has demonstrated that what kids really need if their brains are to develop optimally throughout childhood is lots of interaction with other people. Ideally in the context of unstructured play. Keeping them perpetually spell-bound by computer games, films or cartoons is very much against their best interests.

    telly tubbiesInfants plonked in front of Teletubbies for hours on end are measurably retarded in their language development and verbal expression in comparison to those rarely exposed to screens in their first 2 years of life. This is ironic given that, allegedly, a large team of child psychologists were assembled by the BBC to consult on what elements should be included in order to optimise neurodevelopment.

    Admittedly endless hours of interacting with young kids are shattering. And undoubtedly the most effective method of conjuring some much needed peace and quiet from the endless barrage of questions, perpetual motion, mess, mood swings and tears are screen-based innovations designed specifically to captivate young minds. But the easiest route is rarely the best path and whilst this approach may well be very convenient for frazzled parents it is demonstrably not best for the child.

    Advertisers will jump on any scenario that their intended market might be able to relate to so the theme of pacifying noisy kids with tech is not surprising. Yet it supports the proliferation of lazy, unhelpful parenting tricks that ultimately work against the best interests of a whole generation of humans. Whether or not this amounts to a whole hill of beans in the long run is yet to be seen. Yet from what is known with any certainty so far, there are clear indications that screen time should be monitored and possibly limited, or else it will displace the human face-to-face interactions that so beautifully sculpt young brains in preparation for a long life of interacting with other humans.

    buggy phoneIf you want a child’s neurodevelopment to proceed optimally you should, in my humble opinion, forego the lure of using technological paraphernalia to distract them – unless you are carefully restricting its use at other times – and instead encourage them to engage in some form of play in the real world. And whilst we’re at it you should ensure that as much as possible you give them your full attention. Having your eyes on your smartphone whilst talking to your child is a terrible example to set. So much of communication happens via eye contact and active (as opposed to partially distracted) listening, so if you rob your children of valuable experience with this mode of interaction then their communication skills and social dexterity will suffer.

    I’m not saying people should consign their tablets to the rubbish, nor permanently ban children from using all tech. I’m merely encouraging parents to avoid using these tactics habitually. Save it for when you really need it and you will help your kid to develop the full range of skills, both hard and soft, to give them the best possible start in life.

    And if you think I’m a luddite after this rant you’d be wrong. If you explore my blog further you’ll find plenty of articles relating to the brain benefits of various computer games. Everything in moderation I say (unless we’re talking about working memory training using the Dual N-Back task or reading books in which case I see no harm in overdoing it so long as combined with a healthy social life :-))

    As well as these monthly blogs I do a weekly podcast – Geek Chic’s Weird Science – and daily tweets about breakthroughs in neuroscience and beyond – @drjacklewis.

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  • Dr Jack Lewis – Motivational Speaking Update

    DrJackLewisKeynoteSpeakerI’ve now been on the motivational speaking circuit for over 5 years. I’ve traveled the length and breadth of the country to perform at speaking engagements in schools, science conferences and a wide variety of businesses. As of this year, on the business speaking front, I’ve been very happy to find myself in great demand not just in the U.K. but all over Europe. In light of this I thought I’d write a quick update to describe which topics have been most popular with my clients.

    There is a huge amount of insight that neuroscience can provide on a wide variety of topics. It’s always satisfying to find that, in tailoring my talks to the specific needs of a client, I’m constantly stumbling upon new areas of neuroscientific endeavour with which I wasn’t previously familiar . No matter what the organisation’s priorities have been in terms of what they want their staff to take away from my talk, a few days of digging around in the neuroscience literature ALWAYS yields some inspiration; shedding an interesting new perspective on virtually any topic. Do get in touch if you have a new challenge for me!

     

    Talks for Schools

    Over the past five years I’ve been invited to speak at several different schools across the UK. The aim is to engage young learners, usually in the build up to their big exams, with an upbeat neuroscience narrative that brings to life what exactly is going on inside their brains as they learn. Once students grasp that all their efforts are leading directly to huge changes in the wiring of their brains, adaptations that support the new skills that they are developing through trial and error, their motivation levels invariably rise accordingly.

    I give them insights into straight-forward techniques to get brains working better: whether memorising information more thoroughly, managing exam stress more effectively and simply encouraging them to see school as the only viable way (currently) of sculpting young brains in preparation for dealing with whatever adult life might throw at them. The 2015-2016 school year will be my fifth consecutive year of doing my Brain Coach talk at two of the schools I regularly speak at.

     

    Talks For Business: Neuroscience of Decision Making

    In the last few of years I’ve been working more and more with senior management teams across Europe to help them understand insights from neuroscience that are relevant to their specific business needs. For example, I helped one of Europe’s “Big Four” auditors win a highly lucrative new business contract by sharing with them my Neuroscience of Decision Making talk in the context of reverse engineering the pitch process in light of the flaws in how the human brain evaluates information when making important choices. By exploiting a large corpus of knowledge generated over the past decade or so from neuroeconomic investigations the realities of how risk, uncertainty and benefit are evaluated in the human brain can be explored in order to concoct strategies that improve the likelihood of developing a successful pitch.

     

    Talks for Business: Neuroscience of Creativity

    Since the first outing of my Neuroscience of Creativity talk in 2013 it has evolved into a half-day workshop experience. I’ve been rolling this Innovation Workshop out over the course of 2015 with various members of the Senior Leadership Team at one of the world’s biggest broadcasters by sharing with them everything that science has to offer in terms of techniques that work and those that sound good but ultimately don’t. By assisting them to create an environment that genuinely promotes innovative thinking right at the very top of the organisation and convincing them of the worth of approaches in an evidence-based fashion, the idea is to reduce resistance to some of the seemingly unorthodox strategies in order that they might be allowed to permeate freely throughout the rest of the company.

     

    Sort Your Brain Out

    Sadly many people proclaim that their busy lives simply leave no time to read books. So Adrian Webster and I have turned our book Sort Your Brain Out into a live event. Since our first booking late last year we have been enjoying a steady increase in demand for our motivational speaking duet over the past few months and very much hope that this trend continues in the years to come. We are both represented by Gordon Poole Agency and our speaking agent James Poole is always on hand to discuss booking enquiries.

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